Literature DB >> 3281712

Human muscle glutathione S-transferase (GST-4) shows close homology to human liver GST-1.

P G Board1, T Suzuki, D C Shaw.   

Abstract

Human muscle specific glutathione S-transferase (RX: glutathione R-transferase, EC 2.5.1.18) (GST-4) and liver GST-1 have been purified and subjected to N-terminal sequence analysis. These two isozymes show close homology and only differ in 3 residues within the first 24. The N-terminal sequences of GST-1 and GST-4 differ significantly from those of GST-2 and GST-3. Although antiserum raised against native GST-1 did not cross-react with GST-4, cross-reactivity was obtained with antiserum raised against denatured GST-1. The homology between GST-1 and GST-4 indicates that they are both members of the mu evolutionary class.

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Year:  1988        PMID： 3281712     DOI： 10.1016/0167-4838(88)90027-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  12 in total

1.  Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus.

Authors:  W R Vorachek; W R Pearson; G S Rule
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

2.  Chromosomal localization of human glutathione transferase genes of classes alpha, mu and pi.

Authors:  M Q Islam; A Platz; J Szpirer; C Szpirer; G Levan; B Mannervik
Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

3.  Genetic deficiency of human class mu glutathione S-transferase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z- and E-1,3-dichloropropene.

Authors:  R M Vos; R T van Welie; W H Peters; C T Evelo; J J Boogaards; N P Vermeulen; P J van Bladeren
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

4.  Identification of the trans-stilbene oxide-active glutathione transferase in human mononuclear leukocytes and in liver as GST1.

Authors:  J Seidegård; R W Pero; B Stille
Journal:  Biochem Genet       Date:  1989-04       Impact factor: 1.890

5.  Purification and characterization of acidic glutathione S-transferase 6 from human brain.

Authors:  T Suzuki; D C Shaw; P G Board
Journal:  Biochem J       Date:  1991-03-01       Impact factor: 3.857

6.  The equine major plasma serpin multigene family: partial characterization including sequence of the reactive-site regions.

Authors:  S D Patterson; K Bell; D C Shaw
Journal:  Biochem Genet       Date:  1991-10       Impact factor: 1.890

7.  Glutathione S-transferase class mu in French alcoholic cirrhotic patients.

Authors:  A Groppi; C Coutelle; B Fleury; A Iron; J Begueret; P Couzigou
Journal:  Hum Genet       Date:  1991-09       Impact factor: 4.132

8.  Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.

Authors:  V L Ross; P G Board
Journal:  Biochem J       Date:  1993-09-01       Impact factor: 3.857

9.  Variation in the expression of Mu-class glutathione S-transferase isoenzymes from human skeletal muscle. Evidence for the existence of heterodimers.

Authors:  A J Hussey; L A Kerr; A D Cronshaw; D J Harrison; J D Hayes
Journal:  Biochem J       Date:  1991-01-15       Impact factor: 3.857

10.  The GSTM2 C-Terminal Domain Depresses Contractility and Ca2+ Transients in Neonatal Rat Ventricular Cardiomyocytes.

Authors:  Ruwani P Hewawasam; Dan Liu; Marco G Casarotto; Philip G Board; Angela F Dulhunty
Journal:  PLoS One       Date:  2016-09-09       Impact factor: 3.240
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