Literature DB >> 32812115

Delirium prevalence point: an observational monocentric study in a tertiary university hospital.

Alessandra Negro1, Carlo Leggieri1, Giulia Villa2, Rosalba Lembo1, Federica Signò1, Maria Rosa Lanzalaco1, Lucia Miconi1, Tiziana Tira1, Giuseppe Ponzetta1, Mauro Dossi1, Elisabetta Marzo3, Stefano Rolandi1, Pasqualino D'Aloia1, Duilio Fiorenzo Manara3, Sandro Iannaccone1.   

Abstract

BACKGROUND: Delirium is a serious and common condition that needs an upgrade of the scientific and clinical attention. AIM: To assess the delirium prevalence in an Italian university hospital.
METHODS: The monocentric 1-day observational study cohort has been conducted on March 15, 2018; the population was composed of adult hospitalized patients. All the eligible patients have been evaluated for the presence of delirium with the 4AT.
RESULTS: We enrolled 596 patients. Twenty-nine Acute and 3 Rehabilitation Units were involved in the study. The median age of the sample was 60 (IQR 48-74) and 52% (n = 313) were male. Patients from medical units were 42% (n = 252), from surgery units 41% (n = 249), and from rehabilitation units 15% (n = 95). Results of 4AT showed that 5.4% (n = 32) had delirium (4AT = 4), 12% (n = 73) had cognitive impairment (4AT = 1-3), and 82% (n = 491) had no delirium or cognitive impairment (4AT = 0). We found association between delirium and age, BMI, mortality at 30 days, and hospital mortality. Delirium was related with Barthel Index, dementia, and anticholinesterase inhibitors. About devices in use, we observed a correlation of delirium with central venous catheter, feeding tube, and urinary catheter. Physical restraints were also correlated to delirium.
CONCLUSIONS: We confirmed the presence of delirium across the hospital units, more in medical than in surgical ones. We found associations of delirium with conditions that limit movement, such as dementia, physical restraints, or devices. The development of delirium initiates a cascade of events culminating in the loss of independence and increased morbidity.

Entities:  

Keywords:  Cohort studies; Delirium; Hospitalization; Observational study; Prevalence

Year:  2020        PMID: 32812115     DOI: 10.1007/s11845-020-02348-7

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  1 in total

Review 1.  Cholinesterase inhibitors for the treatment of delirium in non-ICU settings.

Authors:  Ailan Yu; Shanshan Wu; Zongwang Zhang; Tom Dening; Sai Zhao; Gillian Pinner; Jun Xia; Daogui Yang
Journal:  Cochrane Database Syst Rev       Date:  2018-06-28
  1 in total
  2 in total

1.  Delirium in elderly postoperative patients: A prospective cohort study.

Authors:  Chiara Muzzana; Franco Mantovan; Markus Karl Huber; Katia Trevisani; Sarah Niederbacher; Alexander Kugler; Dietmar Ausserhofer
Journal:  Nurs Open       Date:  2022-06-18

2.  Factors associated with post-operative delirium in hip fracture patients: what should we care.

Authors:  Dequn Kong; Weihua Luo; Zhijun Zhu; Sixin Sun; Jian Zhu
Journal:  Eur J Med Res       Date:  2022-03-12       Impact factor: 2.175

  2 in total

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