| Literature DB >> 32811411 |
Esmaeil Sheikh Ahmadi1, Amir Tajbakhsh2, Milad Iranshahy1, Javad Asili1, Nadine Kretschmer3, Abolfazl Shakeri1, Amirhossein Sahebkar4.
Abstract
Naturally occurring naphthoquinones (NQs) comprising highly reactive small molecules are the subject of increasing attention due to their promising biological activities such as antioxidant, antimicrobial, apoptosis-inducing activities, and especially anticancer activity. Lapachol, lapachone, and napabucasin belong to the NQs and are in phase II clinical trials for the treatment of many cancers. This review aims to provide a comprehensive and updated overview on the biological activities of several new NQs isolated from different species of plants reported from January 2013 to January 2020, their potential therapeutic applications and their clinical significance. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: Naphthoquinone; antibacterial; biological activity; cancer; clinical trial; cytotoxic
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Year: 2020 PMID： 32811411 DOI： 10.2174/1389557520666200818212020
Source DB: PubMed Journal: Mini Rev Med Chem ISSN： 1389-5575 Impact factor: 3.862