Literature DB >> 32811173

Diabetes mellitus control in a large cohort of people with HIV in care-Washington, D.C.

David E Wallace1, Michael A Horberg2, Debra A Benator3,4, Alan E Greenberg1, Amanda D Castel1, Anne K Monroe1, Lindsey Powers Happ1.   

Abstract

With more effective antiretroviral therapy (ART), people with HIV (PWH) are living longer and have more chronic diseases, including diabetes mellitus (DM). The prevalence of DM has been estimated in PWH previously, however there is less research regarding DM control. Our objectives were to determine the prevalence of DM and DM control and determine factors associated with DM control in a large urban cohort of PWH in care. We examined DC Cohort participants aged ≥18 years old to determine DM prevalence and to assess DM control (HbA1c measurement <7.0%). Demographic, clinical, and HIV-related factors associated with DM control were identified using multivariate logistic regression. The cohort of 5876 participants was predominantly male (71.3%), Non-Hispanic Black (78.1%) and had a median age of 52.0 years. DM prevalence was 17.4% (1023/5876). Among participants with recent HbA1c data available (39.9%) the proportion with DM control was 60.0% (245/408). In multivariate analysis, higher BMI (aOR: 0.47; 95% CI 0.28, 0.79) and use of non-insulin DM medication (aOR 0.43, 95% CI 0.25, 0.73) or insulin (aOR 0.010, 95% CI 0.04,0.24) compared to no medication use. Our findings suggest that individuals on medication for their DM likely need enhanced support to reach their treatment goals.

Entities:  

Keywords:  Diabetes; Hemoglobin A1c; comorbidities; metabolic

Year:  2020        PMID: 32811173      PMCID: PMC8091517          DOI: 10.1080/09540121.2020.1808160

Source DB:  PubMed          Journal:  AIDS Care        ISSN: 0954-0121


  43 in total

1.  Low-Density Lipoprotein Cholesterol Levels and Statin Treatment by HIV Status Among Multicenter AIDS Cohort Study Men.

Authors:  Anne K Monroe; Wei Fu; Michelle N Zikusoka; Lisa P Jacobson; Mallory D Witt; Frank J Palella; Lawrence A Kingsley; Wendy S Post; Todd T Brown
Journal:  AIDS Res Hum Retroviruses       Date:  2015-03-09       Impact factor: 2.205

2.  Cardiovascular disease and diabetes in HIV-positive and HIV-negative gay and bisexual men over the age of 55 years in Australia: insights from the Australian Positive & Peers Longevity Evaluation Study.

Authors:  R Puhr; K Petoumenos; R Huang; D J Templeton; I Woolley; M Bloch; D Russell; M G Law; D A Cooper
Journal:  HIV Med       Date:  2018-11-26       Impact factor: 3.180

3.  Prevalence of diabetes mellitus and dyslipidemia among antiretroviral naive patients co-infected with hepatitis C virus (HCV) and HIV-1 compared to patients without co-infection.

Authors:  Fehmida Visnegarwala; Li Chen; Subha Raghavan; Ellen Tedaldi
Journal:  J Infect       Date:  2005-05       Impact factor: 6.072

4.  Glycemic control in HIV-infected patients with diabetes mellitus and rates of meeting American Diabetes Association management guidelines.

Authors:  Michael J Satlin; Donald R Hoover; Marshall J Glesby
Journal:  AIDS Patient Care STDS       Date:  2011-01       Impact factor: 5.078

5.  Prevalence, treatment, and control of dyslipidemia and hypertension in 4278 HIV outpatients.

Authors:  Merle Myerson; Eduard Poltavskiy; Ehrin J Armstrong; Shari Kim; Victoria Sharp; Heejung Bang
Journal:  J Acquir Immune Defic Syndr       Date:  2014-08-01       Impact factor: 3.731

6.  Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.

Authors:  R Walli; O Herfort; G M Michl; T Demant; H Jäger; C Dieterle; J R Bogner; R Landgraf; F D Goebel
Journal:  AIDS       Date:  1998-10-22       Impact factor: 4.177

7.  Significant improvement of glycemic control in diabetic patients with HCV infection responding to direct-acting antiviral agents.

Authors:  Alessia Ciancio; Roberta Bosio; Simona Bo; Marianna Pellegrini; Marco Sacco; Edoardo Vogliotti; Giulia Fassio; Andrea G F Bianco Mauthe Degerfeld; Monica Gallo; Chiara Giordanino; Lodovico Terzi di Bergamo; Davide Ribaldone; Elisabetta Bugianesi; Antonina Smedile; Mario Rizzetto; Giorgio Maria Saracco
Journal:  J Med Virol       Date:  2017-11-14       Impact factor: 2.327

8.  HIV infection and glycemic response to newly initiated diabetic medical therapy.

Authors:  Jennifer H Han; Heidi M Crane; Scarlett L Bellamy; Ian Frank; Serena Cardillo; Gregory P Bisson
Journal:  AIDS       Date:  2012-10-23       Impact factor: 4.177

9.  Type 2 diabetes prevalence and its risk factors in HIV: A cross-sectional study.

Authors:  Alastair D Duncan; Louise M Goff; Barry S Peters
Journal:  PLoS One       Date:  2018-03-12       Impact factor: 3.240

10.  A1C underestimates glycemia in HIV infection.

Authors:  Peter S Kim; Christian Woods; Patrick Georgoff; Dana Crum; Alice Rosenberg; Margo Smith; Colleen Hadigan
Journal:  Diabetes Care       Date:  2009-06-05       Impact factor: 19.112

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