Gianfranco Donatelli1, Fabrizio Cereatti2,3, Jean-Loup Dumont2, Nelson Trelles4, Panagiotis Lainas5, Carmelisa Dammaro5, Hadrian Tranchart5, Filippo Pacini6, Roberto Arienzo6, Jean-Marc Chevalier6, David Danan2, Jean-Marc Catheline7, Ibrahim Dagher5. 1. Unité d'Endoscopie Interventionnelle, Hôpital Privé des Peupliers, Ramsay Santé 8 Place de l'Abbé G. Hénocque, 75013, Paris, France. donatelligianfranco@gmail.com. 2. Unité d'Endoscopie Interventionnelle, Hôpital Privé des Peupliers, Ramsay Santé 8 Place de l'Abbé G. Hénocque, 75013, Paris, France. 3. Gastroenterologia ed Endoscopia Digestiva ASST Cremona, Cremona, Italy. 4. Service de Chirugie Générale et Digestive, Centre Hospitalier Rene Dubos, Pontoise, France. 5. Department of Minimally Invasive Digestive Surgery, Antoine Beclere Hospital AP-HP, Clamart, France. 6. Centre Obésité Paris Peupliers, Hôpital Privé des Peupliers, Ramsay Santé, Paris, France. 7. Department of Digestive Surgery, Centre Hospitalier de Saint-Denis, Saint-Denis, France.
Abstract
BACKGROUND: Submucosal tumors (SMTs) of the gastrointestinal tract are a rare pathological entity comprising a wide variety of neoplastic and non-neoplastic lesions. Even if most SMTs are benign tumors (e.g., leiomyomas), a smaller portion may have a malignant potential (e.g., gastrointestinal stromal tumor (GIST)). Preoperative diagnosis of SMT in bariatric patients may arise challenging clinical dilemmas. Long-term surveillance may be difficult after bariatric surgery. Moreover, according to SMT location, its presence may interfere with planned surgery. Submucosal tunneling endoscopic resection (STER) has emerged as an effective approach for minimally invasive en bloc excision of SMTs. This is the first case series of STER for SMTs before bariatric surgery. METHODS: Seven female patients underwent STER for removal of SMTs before bariatric surgery. All lesions were incidentally diagnosed at preoperative endoscopy. STER procedural steps comprised mucosal incision, submucosal tunneling, lesion enucleation, and closure of mucosal defect. RESULTS: En bloc removal of SMT was achieved in all cases. Mean procedural time was of 45 min (SD 18.6). No adverse event occurred. Mean size of the lesions was 20.6 mm (SD 5.8). Histological diagnoses were 5 leyomiomas, 1 lipoma, and 1 low grade GIST. Bariatric procedure was performed after a mean period of 4.1 months (SD 1.6) from endoscopic resection. CONCLUSION: STER is a safe and effective treatment for the management of SMT even in bariatric patients awaiting surgery. Preoperative endoscopic resection of SMTs has the advantages of reducing the need for surveillance and removing lesions that could interfere with planned surgery. STER did not altered accomplishment of bariatric procedures.
BACKGROUND:Submucosal tumors (SMTs) of the gastrointestinal tract are a rare pathological entity comprising a wide variety of neoplastic and non-neoplastic lesions. Even if most SMTs are benign tumors (e.g., leiomyomas), a smaller portion may have a malignant potential (e.g., gastrointestinal stromal tumor (GIST)). Preoperative diagnosis of SMT in bariatric patients may arise challenging clinical dilemmas. Long-term surveillance may be difficult after bariatric surgery. Moreover, according to SMT location, its presence may interfere with planned surgery. Submucosal tunneling endoscopic resection (STER) has emerged as an effective approach for minimally invasive en bloc excision of SMTs. This is the first case series of STER for SMTs before bariatric surgery. METHODS: Seven female patients underwent STER for removal of SMTs before bariatric surgery. All lesions were incidentally diagnosed at preoperative endoscopy. STER procedural steps comprised mucosal incision, submucosal tunneling, lesion enucleation, and closure of mucosal defect. RESULTS: En bloc removal of SMT was achieved in all cases. Mean procedural time was of 45 min (SD 18.6). No adverse event occurred. Mean size of the lesions was 20.6 mm (SD 5.8). Histological diagnoses were 5 leyomiomas, 1 lipoma, and 1 low grade GIST. Bariatric procedure was performed after a mean period of 4.1 months (SD 1.6) from endoscopic resection. CONCLUSION:STER is a safe and effective treatment for the management of SMT even in bariatric patients awaiting surgery. Preoperative endoscopic resection of SMTs has the advantages of reducing the need for surveillance and removing lesions that could interfere with planned surgery. STER did not altered accomplishment of bariatric procedures.
Authors: Jocelyn T Mendes; Christopher Wilson; Christine M G Schammel; John D Scott; David P Schammel; Steven D Trocha Journal: Surg Obes Relat Dis Date: 2019-11-18 Impact factor: 4.734
Authors: Manish Parikh; Jennifer Liu; Dorice Vieira; Demetrios Tzimas; Daniel Horwitz; Andrew Antony; John K Saunders; Akuezunkpa Ude-Welcome; Adam Goodman Journal: Obes Surg Date: 2016-12 Impact factor: 4.129