Juhua Luo1, Xiwei Chen2, Hilary Tindle3, Aladdin H Shadyab4, Nazmus Saquib5, Lauren Hale6, Lorena Garcia7, Sparkle Springfield8, Buyun Liu9, Rami Nassir10, Linda Snetselaar11, Michael Hendryx12. 1. Department of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, IN. Electronic address: juhluo@indiana.edu. 2. Department of Epidemiology and Biostatistics, School of Public Health, Indiana University Bloomington, Bloomington, IN. 3. Department of Medicine, Vanderbilt Univeristy, Nashville, TN. 4. Department of Family Medicine and Public Health, University of California, San Diego School of Medicine, La Jolla. 5. Research Unit, College of Medicine, Sulaiman AlRajhi University, Saudi Arabia. 6. Department of Family, Population and Preventive Medicine, School of Medicine, Stony Brook University, NY. 7. Department of Public Health Sciences, School of Medicine University of California, Davis. 8. Department of Public Health, Parkinson School of Health Sciences and Public Health, Loyola University Chicago, Maywood, IL. 9. Department of Epidemiology, College of Public Health, University of Iowa, IA. 10. Department of Pathology, School of Medicine, Umm Al-Qura University, Saudi Arabia. 11. Department of Epidemiology, College of Public Health, Univeristy of Iowa, IA. 12. Department of Environmental and Occupational Health, School of Public Health, Indiana University Bloomington, Bloomington, IN.
Abstract
PURPOSE: Personality traits have been reported to be associated with type 2 diabetes (T2DM) risk. The objective of this study was to examine whether and to what extent the associations between personality traits (dispositional optimism, hostility, and negative emotional expressiveness) and risk of T2DM were mediated by health behaviors and obesity. METHODS: Postmenopausal women (n = 110,992) aged 50-79 years without diabetes at enrollment in the Women's Health Initiative study (1993-1998) were followed up to 25 years. Incident diabetes was assessed via a validated self-report of physician-diagnosed diabetes treated with insulin or other hypoglycemic medications. Mediation analyses were performed using approaches under a counterfactual framework. RESULTS: An inverse association of optimism with diabetes was significantly mediated by a factor primarily extracted from physical activity, diet quality, and sleep quality with a mediated proportion of 28%. Positive associations for hostility and negative emotional expressiveness were substantially mediated by a factor primarily composed of body mass index and waist circumference with mediated proportions of 32% and 44%, respectively. CONCLUSIONS: Our data revealed that less than half of the associations between personality traits and risk of T2DM were explained by indirect health behavior pathways. Women's personality traits should be considered in prevention of diabetes in addition to promoting health behaviors.
PURPOSE: Personality traits have been reported to be associated with type 2 diabetes (T2DM) risk. The objective of this study was to examine whether and to what extent the associations between personality traits (dispositional optimism, hostility, and negative emotional expressiveness) and risk of T2DM were mediated by health behaviors and obesity. METHODS: Postmenopausal women (n = 110,992) aged 50-79 years without diabetes at enrollment in the Women's Health Initiative study (1993-1998) were followed up to 25 years. Incident diabetes was assessed via a validated self-report of physician-diagnosed diabetes treated with insulin or other hypoglycemic medications. Mediation analyses were performed using approaches under a counterfactual framework. RESULTS: An inverse association of optimism with diabetes was significantly mediated by a factor primarily extracted from physical activity, diet quality, and sleep quality with a mediated proportion of 28%. Positive associations for hostility and negative emotional expressiveness were substantially mediated by a factor primarily composed of body mass index and waist circumference with mediated proportions of 32% and 44%, respectively. CONCLUSIONS: Our data revealed that less than half of the associations between personality traits and risk of T2DM were explained by indirect health behavior pathways. Women's personality traits should be considered in prevention of diabetes in addition to promoting health behaviors.
Authors: Narges Mohammadi; Alireza Aghayousefi; Gholam Reza Nikrahan; Caitlin N Adams; Ahmad Alipour; Masoumeh Sadeghi; Hamidreza Roohafza; Christopher M Celano; Jeff C Huffman Journal: Gen Hosp Psychiatry Date: 2017-12-19 Impact factor: 3.238
Authors: Brent W Roberts; Jing Luo; Daniel A Briley; Philip I Chow; Rong Su; Patrick L Hill Journal: Psychol Bull Date: 2017-01-05 Impact factor: 17.737
Authors: Hermann Nabi; Mika Kivimaki; Séverine Sabia; Aline Dugravot; Mohamed Lajnef; Michael G Marmot; Archana Singh-Manoux Journal: Am J Epidemiol Date: 2008-11-20 Impact factor: 4.897
Authors: Ana M Progovac; Julie M Donohue; Karen A Matthews; Chung-Chou H Chang; Elizabeth B Habermann; Lewis H Kuller; Juliann Saquib; Michael J LaMonte; Elena Salmoirago-Blotcher; Oleg Zaslavsky; Hilary A Tindle Journal: Prev Med Rep Date: 2017-10-16
Authors: Karen L Margolis; Robert Brzyski; Denise E Bonds; Barbara V Howard; Sarah Kempainen; Jennifer G Robinson; Monika M Safford; Lesley T Tinker; Lawrence S Phillips Journal: Clin Trials Date: 2008 Impact factor: 2.486