Literature DB >> 3280373

Insulin release by glucose anomers in a rat model of non-insulin-dependent diabetes.

A Niki1, H Niki, I Niki, Y Kunoh.   

Abstract

The effects of the alpha and beta anomers of D-glucose on insulin release were studied in a rat model of non-insulin-dependent diabetes, which was induced by streptozotocin injection at 2 days of age. Glucose tolerance of the streptozotocin-treated rats at 8-10 weeks of age was mildly diabetic. Insulin release from the isolated perfused pancreas of the diabetic rats in response to 10 mmol/l alpha-D-glucose was markedly impaired, while insulin response to 10 mmol/l beta-D-glucose in the diabetic pancreas was only slightly reduced as compared to that in the control pancreas.

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Year:  1988        PMID： 3280373     DOI： 10.1007/bf00279137

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  8 in total

Review 1.  Anomeric specificity of hexose metabolism in pancreatic islets.

Authors:  W J Malaisse; F Malaisse-Lagae; A Sener
Journal:  Physiol Rev       Date:  1983-07       Impact factor: 37.312

2.  Effect of anomers of D-mannose on insulin release from perfused rat pancreas.

Authors:  A Niki; H Niki; I Miwa
Journal:  Endocrinology       Date:  1979-11       Impact factor: 4.736

3.  Islet secretion in a new experimental model for non-insulin-dependent diabetes.

Authors:  G C Weir; E T Clore; C J Zmachinski; S Bonner-Weir
Journal:  Diabetes       Date:  1981-07       Impact factor: 9.461

4.  Responses of neonatal rat islets to streptozotocin: limited B-cell regeneration and hyperglycemia.

Authors:  S Bonner-Weir; D F Trent; R N Honey; G C Weir
Journal:  Diabetes       Date:  1981-01       Impact factor: 9.461

5.  Glucose utilization in islets of hyperglycemic rat models with impaired glucose-induced insulin secretion.

Authors:  R M Colella; J M May; S Bonner-Weir; J L Leahy; G C Weir
Journal:  Metabolism       Date:  1987-04       Impact factor: 8.694

6.  Pathophysiology of insulin secretion in non-insulin-dependent diabetes mellitus.

Authors:  W K Ward; J C Beard; J B Halter; M A Pfeifer; D Porte
Journal:  Diabetes Care       Date:  1984 Sep-Oct       Impact factor: 19.112

Review 7.  New perspectives on pancreatic islet glucokinase.

Authors:  M D Meglasson; F M Matschinsky
Journal:  Am J Physiol       Date:  1984-01

8.  Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.

Authors:  M H Giroix; B Portha; M Kergoat; D Bailbe; L Picon
Journal:  Diabetes       Date:  1983-05       Impact factor: 9.461
  8 in total
  5 in total

1.  Altered anomeric specificity of glucose-induced insulin release in rabbits with duct-ligated pancreas.

Authors:  F Fichaux; J Marchand; B Yaylali; V Leclercq-Meyer; J Catala; W J Malaisse
Journal:  Int J Pancreatol       Date:  1991-02

2.  Electrophysiology of the pancreatic islet β-cell sweet taste receptor TIR3.

Authors:  Juan V Sanchez-Andres; Willy J Malaisse; Itaru Kojima
Journal:  Pflugers Arch       Date:  2018-12-14       Impact factor: 3.657

3.  Role of glycogen metabolism in pancreatic islet beta cell function.

Authors:  Willy J Malaisse
Journal:  Diabetologia       Date:  2016-08-27       Impact factor: 10.122

Review 4.  Enzyme-to-enzyme channeling in the early steps of glycolysis in rat pancreatic islets.

Authors:  Willy J Malaisse; Ying Zhang; Abdullah Sener
Journal:  Endocrine       Date:  2004-07       Impact factor: 3.633

Review 5.  Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cells.

Authors:  Itaru Kojima; Yuko Nakagawa; Yoshiaki Ohtsu; Kunihisa Hamano; Johan Medina; Masahiro Nagasawa
Journal:  J Diabetes Investig       Date:  2014-12-15       Impact factor: 4.232
  5 in total

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