Harmful Cyanobacterial Blooms (HCBs): innovative green bioremediation process based on anti-cyanobacteria bioactive natural products.

Over the last decades, Harmful Cyanobacterial Blooms (HCBs) represent one of the most conspicuous hazards to human health in freshwater ecosystems, due to the uses of the water for drinking, recreation and aquaculture. Cyanobacteria are one of the main biological components in freshwater ecosystems and they may proliferate in nutrients rich ecosystems causing severe impacts at different levels. Therefore, several methods have been applied to control cyanobacterial proliferation, including physical, chemical and biological strategies. However, the application of those methods is generally not very efficient. Research on an eco-friendly alternative leading to the isolation of new bioactive compounds with strong impacts against harmful cyanobacteria is a need in the field of water environment protection. Thus, this paper aims to give an overview of harmful cyanobacterial blooms and reviews the state of the art of studying the activities of biological compounds obtained from plants, seaweeds and microorganisms in the cyanobacterial bloom control.