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Literature DB >> 328024

Massive digoxin ingestion. Report of a case and review of currently available therapies.

Abstract

Recent reports of treatment of massive digoxin overdosage have emphasized the success of medical therapy. This report describes a fatal outcome to this problem despite aggressive medical management, including pervenous cardiac pacing and draws attention to deficiencies in current treatment of a serious problem.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1977 PMID： 328024 PMCID： PMC483300 DOI： 10.1136/hrt.39.6.688

Source DB: PubMed Journal: Br Heart J ISSN： 0007-0769

22 in total

1. CARDIAC ARRHYTHMIAS FOLLOWING CONDENSER DISCHARGES AND THEIR DEPENDENCE UPON STRENGTH OF CURRENT AND PHASE OF CARDIAC CYCLE.

Authors: B PELESKA
Journal: Circ Res Date: 1963-07 Impact factor: 17.367

2. Post-countershock arrhythmias in untreated and digitalized dogs.

Authors: R E Ten Eick; S R Wyte; S M Ross; B F Hoffman
Journal: Circ Res Date: 1967-09 Impact factor: 17.367

3. [Hyperkalemia in massive digitalis intoxication. Prognostic value and therapeutic implications].

Authors: C Bismuth; G Motté; J P Fréjaville; F Conso
Journal: Arch Mal Coeur Vaiss Date: 1973-12

Review 4. The subcellular basis for the mechanism of inotropic action of cardiac glycosides.

Authors: K S Lee; W Klaus
Journal: Pharmacol Rev Date: 1971-09 Impact factor: 25.468

Review 5. Current concepts and treatment of digitalis toxicity.

Authors: D T Mason; R Zelis; G Lee; J L Hughes; J F Spann; E A Amsterdam
Journal: Am J Cardiol Date: 1971-05 Impact factor: 2.778

6. Interaction of epinephrine and ouabain on automaticity of canine Purkinje fibers.

Authors: W W Tse; J Han
Journal: Circ Res Date: 1974-06 Impact factor: 17.367

Review 7. Review: Electrolyte and antiarrhythmic drug interaction.

Authors: L S Dreifus; I M de Azevedo; Y Watanabe
Journal: Am Heart J Date: 1974-07 Impact factor: 4.749

8. Effect of ouabain and its interaction with diphenylhydantoin on cardiac arrhythmias induced by hypothalamic stimulation.

Authors: D E Evans; R A Gillis
Journal: J Pharmacol Exp Ther Date: 1975-12 Impact factor: 4.030

Massive digoxin ingestion. Report of a case and review of currently available therapies.

1. CARDIAC ARRHYTHMIAS FOLLOWING CONDENSER DISCHARGES AND THEIR DEPENDENCE UPON STRENGTH OF CURRENT AND PHASE OF CARDIAC CYCLE.

2. Post-countershock arrhythmias in untreated and digitalized dogs.

3. [Hyperkalemia in massive digitalis intoxication. Prognostic value and therapeutic implications].

Review 4. The subcellular basis for the mechanism of inotropic action of cardiac glycosides.

Review 5. Current concepts and treatment of digitalis toxicity.

6. Interaction of epinephrine and ouabain on automaticity of canine Purkinje fibers.

Review 7. Review: Electrolyte and antiarrhythmic drug interaction.

8. Effect of ouabain and its interaction with diphenylhydantoin on cardiac arrhythmias induced by hypothalamic stimulation.

9. Disorders of impulse conduction and impulse formation caused by hyperkalemia in man.

10. Phenytoin (diphenylhydantoin) treatment of massive digoxin overdose.

1. Use of amiodarone and digoxin specific Fab antibodies in digoxin overdosage.

2. Massive digoxin overdose: successful treatment with intravenous amiodarone.

3. Digitalis toxicity in infants and children.

4. Mistaken ST-Elevation Myocardial Infarction.