Literature DB >> 3280194

Oncogene expression in related cancer lines differing in metastatic capacity.

J Pohl1, A Radler-Pohl, R Heicappell, V Schirrmacher.   

Abstract

Various murine tumor cell lines with different metastatic capacities were tested in vitro for oncogene expression, especially of the p21-Ha-ras protein. Small differences were seen in the expression of several distinct oncogenes in the case of a high metastatic lymphoma variant (ESb) and its low metastatic parental line (Eb). In one instance we observed a 30-fold Ha-ras gene amplification in a metastasis-derived cell line from a spontaneous mouse mammary carcinoma. In spite of this amplification we did not find an increased p21 expression in these cells.

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Year:  1988        PMID： 3280194     DOI： 10.1007/bf01782480

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN： 0262-0898            Impact factor:   5.150


  46 in total

1.  The action of oncogenes in the cytoplasm and nucleus.

Authors:  R A Weinberg
Journal:  Science       Date:  1985-11-15       Impact factor: 47.728

2.  Expression of ki-ras oncogene in tumor cell variants exhibiting different metastatic capabilities.

Authors:  R M Kris; A Avivi; M Bar-Eli; Y Alon; P Carmi; J Schlessinger; A Raz
Journal:  Int J Cancer       Date:  1985-02-15       Impact factor: 7.396

3.  Antigenic variation in cancer metastasis: immune escape versus immune control.

Authors:  V Schirrmacher; M Fogel; E Russmann; K Bosslet; P Altevogt; L Beck
Journal:  Cancer Metastasis Rev       Date:  1982       Impact factor: 9.264

4.  Experimental metastatic ability of H-ras-transformed NIH3T3 cells.

Authors:  G P Bondy; S Wilson; A F Chambers
Journal:  Cancer Res       Date:  1985-12       Impact factor: 12.701

5.  Harvey ras induction of metastatic potential depends upon oncogene activation and the type of recipient cell.

Authors:  R J Muschel; J E Williams; D R Lowy; L A Liotta
Journal:  Am J Pathol       Date:  1985-10       Impact factor: 4.307

6.  Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family.

Authors:  M E Furth; L J Davis; B Fleurdelys; E M Scolnick
Journal:  J Virol       Date:  1982-07       Impact factor: 5.103

7.  McDonough feline sarcoma virus: characterization of the molecularly cloned provirus and its feline oncogene (v-fms).

Authors:  L Donner; L A Fedele; C F Garon; S J Anderson; C J Sherr
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

8.  Avian myeloblastosis virus transforming gene is related to unique chicken DNA regions separated by at least one intervening sequence.

Authors:  B Perbal; M A Baluda
Journal:  J Virol       Date:  1982-01       Impact factor: 5.103

9.  Molecular cloning of Snyder-Theilen feline leukemia and sarcoma viruses: comparative studies of feline sarcoma virus with its natural helper virus and with Moloney murine sarcoma virus.

Authors:  C J Sherr; L A Fedele; M Oskarsson; J Maizel; G Vande Woude
Journal:  J Virol       Date:  1980-04       Impact factor: 5.103

10.  Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus.

Authors:  U R Rapp; M D Goldsborough; G E Mark; T I Bonner; J Groffen; F H Reynolds; J R Stephenson
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205
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  2 in total

1.  Ras levels and metalloproteinase activity in normal versus neoplastic rat mammary tissues.

Authors:  M Ballin; A R Mackay; J L Hartzler; A Nason; M D Pelina; U P Thorgeirsson
Journal:  Clin Exp Metastasis       Date:  1991 Mar-Apr       Impact factor: 5.150

2.  Cyclic AMP decreases chemotaxis, invasiveness and lung colonization of H-ras transformed mouse fibroblasts.

Authors:  Y Iwamoto; R Reich; G Nemeth; Y Yamada; G R Martin
Journal:  Clin Exp Metastasis       Date:  1993-11       Impact factor: 5.150
  2 in total

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