| Literature DB >> 32799339 |
Xu Gao1, Weining Shen1, Liwen Zhang2, Jianhua Hu3, Norbert J Fortin4, Ron D Frostig4,5, Hernando Ombao6.
Abstract
We propose a novel regularized mixture model for clustering matrix-valued data. The proposed method assumes a separable covariance structure for each cluster and imposes a sparsity structure (eg, low rankness, spatial sparsity) for the mean signal of each cluster. We formulate the problem as a finite mixture model of matrix-normal distributions with regularization terms, and then develop an expectation maximization type of algorithm for efficient computation. In theory, we show that the proposed estimators are strongly consistent for various choices of penalty functions. Simulation and two applications on brain signal studies confirm the excellent performance of the proposed method including a better prediction accuracy than the competitors and the scientific interpretability of the solution.Entities:
Keywords: clustering; imaging; matrix normal distribution; mixture model; regularization; time-frequency analysis
Mesh:
Year: 2020 PMID: 32799339 PMCID: PMC7884484 DOI: 10.1111/biom.13354
Source DB: PubMed Journal: Biometrics ISSN: 0006-341X Impact factor: 1.701