Alcohol intolerance in the hypereosinophilic syndrome.

Alcohol intolerance presented as an initial symptom in two patients with hypereosinophilic syndrome. In patient 1 alcohol intolerance persisted during the whole course of disease, while in patient 2 all symptoms including alcohol intolerance disappeared after treatment with prednisolone and vincristine. Alcohol intolerance seems to be influenced by hypereosinophilia and may be of clinical value in the evaluation of the activity of the malignant disorder.