Literature DB >> 32798209

Reinventing Molecular Imaging with Total-Body PET, Part I: Technical Revolution in Evolution.

Babak Saboury1, Michael A Morris2, Faraz Farhadi3, Moozhan Nikpanah3, Thomas J Werner4, Elizabeth C Jones3, Abass Alavi4.   

Abstract

Total-body PET (TB-PET) is a technical advancement providing improved signal detection (effective sensitivity). This is achieved through a novel extended detector geometry among many other fine attunements. This technical evolution will ripple through molecular imaging revolutionizing clinical practice beyond the expectations of its designers. This article explores how this leap forward in effective sensitivity through TB-PET could enable dose reduction, faster imaging, temporal resolution improvement, dynamic imaging, and the in vivo noninvasive study of clinical systems biology. TB-PET has the potential to be an enabler of disruptive innovations in molecular imaging. This will change the landscape of medical imaging. Published by Elsevier Inc.

Entities:  

Keywords:  Molecular imaging; Parametric PET; Radiophenomics; Systems biology; Total-body PET

Mesh：

Year:  2020        PMID： 32798209     DOI： 10.1016/j.cpet.2020.06.012

Source DB:  PubMed          Journal:  PET Clin        ISSN： 1556-8598


  7 in total

Review 1.  Artificial Intelligence in Medical Imaging and its Impact on the Rare Disease Community: Threats, Challenges and Opportunities.

Authors:  Navid Hasani; Faraz Farhadi; Michael A Morris; Moozhan Nikpanah; Arman Rhamim; Yanji Xu; Anne Pariser; Michael T Collins; Ronald M Summers; Elizabeth Jones; Eliot Siegel; Babak Saboury
Journal:  PET Clin       Date:  2022-01

2.  Total-body [18F]FDG PET/CT scan has stepped into the arena: the faster, the better. Is it always true?

Authors:  Luca Filippi; Orazio Schillaci
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-08       Impact factor: 10.057

3.  Can Target-to-Background Ratio Measurement Lead to Detection and Accurate Quantification of Atherosclerosis With FDG PET? Likely Not.

Authors:  Abass Alavi; Thomas J Werner; Poul Flemming Høilund-Carlsen; Mona-Elisabeth Revheim
Journal:  Clin Nucl Med       Date:  2022-04-05       Impact factor: 10.782

Review 4.  Mars Shot for Nuclear Medicine, Molecular Imaging, and Molecularly Targeted Radiopharmaceutical Therapy.

Authors:  Richard L Wahl; Panithaya Chareonthaitawee; Bonnie Clarke; Alexander Drzezga; Liza Lindenberg; Arman Rahmim; James Thackeray; Gary A Ulaner; Wolfgang Weber; Katherine Zukotynski; John Sunderland
Journal:  J Nucl Med       Date:  2021-01       Impact factor: 11.082

5.  A Systems-Level Analysis of Total-Body PET Data Reveals Complex Skeletal Metabolism Networks in vivo.

Authors:  Karla J Suchacki; Carlos J Alcaide-Corral; Samah Nimale; Mark G Macaskill; Roland H Stimson; Colin Farquharson; Tom C Freeman; Adriana A S Tavares
Journal:  Front Med (Lausanne)       Date:  2021-09-20

Review 6.  Advantages and Applications of Total-Body PET Scanning.

Authors:  Sanaz Katal; Liesl S Eibschutz; Babak Saboury; Ali Gholamrezanezhad; Abass Alavi
Journal:  Diagnostics (Basel)       Date:  2022-02-07

Review 7.  Parathyroid Imaging: Past, Present, and Future.

Authors:  Michael A Morris; Babak Saboury; Mark Ahlman; Ashkan A Malayeri; Elizabeth C Jones; Clara C Chen; Corina Millo
Journal:  Front Endocrinol (Lausanne)       Date:  2022-02-25       Impact factor: 5.555
  7 in total

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