Literature DB >> 32785359

Enzyme catalysis powered micro/nanomotors for biomedical applications.

Motilal Mathesh1, Jiawei Sun, Daniela A Wilson.   

Abstract

With recent developments in the field of autonomous motion for artificial systems, many researchers are focusing on their biomedical application for active and targeted delivery. In this context, enzyme powered motors are at the forefront since they can utilize physiologically relevant fuels as their substrate and carry out catalytic reactions to power motion under in vivo conditions. This review focuses on the design and fabrication of enzyme powered motors together with their propulsion mechanism by using fuels present in biological environments. In addition, the recent advances in the field of enzyme powered motors for biomedical applications have been discussed together with the parameters that need to be considered for designing such systems. We believe that this review will provide insights and better understanding for the development of next generation biomedical technologies based on enzyme powered motors.

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Year:  2020        PMID: 32785359     DOI: 10.1039/d0tb01245a

Source DB:  PubMed          Journal:  J Mater Chem B        ISSN: 2050-750X            Impact factor:   6.331


  5 in total

1.  Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers.

Authors:  Serena Arnaboldi; Gerardo Salinas; Aleksandar Karajić; Patrick Garrigue; Tiziana Benincori; Giorgia Bonetti; Roberto Cirilli; Sabrina Bichon; Sébastien Gounel; Nicolas Mano; Alexander Kuhn
Journal:  Nat Chem       Date:  2021-10-14       Impact factor: 24.427

2.  Protein Based Biomaterials for Therapeutic and Diagnostic Applications.

Authors:  Stanley Chu; Andrew L Wang; Aparajita Bhattacharya; Jin Kim Montclare
Journal:  Prog Biomed Eng (Bristol)       Date:  2021-10-26

3.  Enzyme Purification Improves the Enzyme Loading, Self-Propulsion, and Endurance Performance of Micromotors.

Authors:  Morgane Valles; Sílvia Pujals; Lorenzo Albertazzi; Samuel Sánchez
Journal:  ACS Nano       Date:  2022-03-28       Impact factor: 18.027

Review 4.  Enzyme-powered micro- and nano-motors: key parameters for an application-oriented design.

Authors:  Xavier Arqué; Tania Patiño; Samuel Sánchez
Journal:  Chem Sci       Date:  2022-07-21       Impact factor: 9.969

5.  Ceruloplasmin in flatland: the relationship between enzyme catalytic activity and surface hydrophilicity.

Authors:  Agata Kowalczyk; Cong Yu; Anna M Nowicka
Journal:  RSC Adv       Date:  2022-09-06       Impact factor: 4.036

  5 in total

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