José María Vieitez1, Juan Manuel Monteagudo1, Patricia Mahia2, Leopoldo Perez2, Teresa Lopez3, Irene Marco3, Francesco Perone3, Teresa González4, Marta Sitges5, Alberto Bouzas6, Violeta González-Salvado7, Chi-Hion Li8, David Alonso9, Fernando Carrasco10, Antonio Adeba11, Jesus Maria de la Hera11, Covadonga Fernandez-Golfin1, José Luis Zamorano1,12. 1. Department of Cardiology, CIBERCV University Hospital Ramon y Cajal, Carretera de Colmenar Km 9.100, Madrid 28034, Spain. 2. Department of Cardiology, Hospital Clinic San Carlos, calle Prof Martín Lagos, Madrid 28040, Spain. 3. Department of Cardiology, University Hospital La Paz, Paseo de la Castellana, 261, Madrid 28046, Spain. 4. Department of Cardiology, Hospital Vall d`Hebron, Passeig de la Vall d'Hebron, 119, 129, Barcelona, Spain. 5. Barcelona Hospital Clinic de Barcelona, Carrer de Villarroel 170, Barcelona 08036, Spain. 6. Department of Cardiology, University Hospital Complex A Coruña, As Xubias 84, A Coruña 15006, Spain. 7. Hospital Clínico Universitario de Santiago de Compostela, IDIS (CIBERCV) 8. Department of Cardiology, Hospital of Santa Creu I Sant Pau, Carrer de Sant Quintí, 89, Barcelona 08041, Spain 9. Department of Cardiology, Hospital of Leon, Altos de Nava, León 24008, Spain. 10. Department of Cardiology, University Hospital Virgen de la Victoria, Campus de Teatinos, Málaga 29010, Spain. 11. Department of Cardiology, University Hospital Central de Asturias, Avenida de Roma s/n, Oviedo 33011, Spain. 12. Department of Cardiology, La Zarzuela Hospital, Calle de Pleyades, 25, Madrid 28023, Spain.
Abstract
AIMS: To evaluate the burden of tricuspid regurgitation (TR) in a large cohort, determine the right ventricle involvement of patients with TR and determine the characteristics of isolated TR. METHODS AND RESULTS: Prospective study where consecutive patients undergoing an echocardiographic study in 10 centres were included. All studies with significant TR (at least moderate) were selected. We considered that patients with one of pulmonary systolic hypertension >50 mmHg, left ventricular ejection fraction <35%, New York Heart Association III-IV, or older than 85 years, had a high surgical risk. A total of 35 088 echocardiograms were performed. Significant TR was detected in 6% of studies. Moderate TR was found in 69.6%, severe in 25.5%, massive in 3.9%, and torrential in 1.0% of patients. Right ventricle was dilated in 81.7% of patients with massive/torrential TR, in 55.9% with severe TR, and in 29.3% with moderate TR (P < 0.001). Primary TR was present in 7.4% of patients whereas secondary TR was present in 92.6%. Mitral or aortic valve disease was the most common aetiology (54.6%), following by isolated TR (16%). Up to 51.9% of patients with severe, massive, or torrential primary TR and 57% of patients with severe, massive, or torrential secondary TR had a high surgical risk. CONCLUSION: Significant TR is a prevalent condition and a high proportion of these patients have an indication for valve intervention. More than a half of patients with severe, massive, or torrential TR had a high surgical risk. Massive/torrential TR may have implications regarding selection and monitoring patients for percutaneous treatment. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: To evaluate the burden of tricuspid regurgitation (TR) in a large cohort, determine the right ventricle involvement of patients with TR and determine the characteristics of isolated TR. METHODS AND RESULTS: Prospective study where consecutive patients undergoing an echocardiographic study in 10 centres were included. All studies with significant TR (at least moderate) were selected. We considered that patients with one of pulmonary systolic hypertension >50 mmHg, left ventricular ejection fraction <35%, New York Heart Association III-IV, or older than 85 years, had a high surgical risk. A total of 35 088 echocardiograms were performed. Significant TR was detected in 6% of studies. Moderate TR was found in 69.6%, severe in 25.5%, massive in 3.9%, and torrential in 1.0% of patients. Right ventricle was dilated in 81.7% of patients with massive/torrential TR, in 55.9% with severe TR, and in 29.3% with moderate TR (P < 0.001). Primary TR was present in 7.4% of patients whereas secondary TR was present in 92.6%. Mitral or aortic valve disease was the most common aetiology (54.6%), following by isolated TR (16%). Up to 51.9% of patients with severe, massive, or torrential primary TR and 57% of patients with severe, massive, or torrential secondary TR had a high surgical risk. CONCLUSION: Significant TR is a prevalent condition and a high proportion of these patients have an indication for valve intervention. More than a half of patients with severe, massive, or torrential TR had a high surgical risk. Massive/torrential TR may have implications regarding selection and monitoring patients for percutaneous treatment. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Anna Sannino; Federica Ilardi; Rebecca T Hahn; Patrizio Lancellotti; Philipp Lurz; Robert L Smith; Giovanni Esposito; Paul A Grayburn Journal: Front Cardiovasc Med Date: 2022-07-11
Authors: Susanne Anna Schlossbauer; Francesco Fulvio Faletra; Vera Lucia Paiocchi; Laura Anna Leo; Giorgio Franciosi; Michela Bonanni; Gianmarco Angelini; Anna Giulia Pavon; Enrico Ferrari; Siew Yen Ho; Rebecca T Hahn Journal: J Cardiovasc Dev Dis Date: 2021-09-03