Literature DB >> 3278170

The role of epsilon-aminocaproic acid in reducing bleeding after cardiac operation: a double-blind randomized study.

T J Vander Salm1, J E Ansell, O N Okike, T H Marsicano, R Lew, W P Stephenson, K Rooney.   

Abstract

Sixty patients scheduled for elective coronary artery bypass graft operations were randomly assigned to receive epsilon-aminocaproic acid or placebo to test whether antifibrinolytic therapy would decrease postoperative bleeding. A small but significant decrease in bleeding was observed in the treated group without complications resulting from treatment with epsilon-aminocaproic acid.

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Year:  1988        PMID: 3278170

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  10 in total

1.  Effect of tranexamic acid on blood loss reduction after cardiopulmonary bypass.

Authors:  Y Uozaki; G Watanabe; K Kotou; K Ueyama; Y Doi; T Misaki
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  2001-05

Review 2.  The hemostatic defect of cardiopulmonary bypass.

Authors:  Matthew Dean Linden
Journal:  J Thromb Thrombolysis       Date:  2003-12       Impact factor: 2.300

3.  Effective haemostasis during cardiac surgery.

Authors:  J C Horrow; N Ellison
Journal:  Can J Anaesth       Date:  1992-04       Impact factor: 5.063

Review 4.  Natural and synthetic antifibrinolytics in adult cardiac surgery: efficacy, effectiveness and efficiency.

Authors:  J F Hardy; S Bélisle
Journal:  Can J Anaesth       Date:  1994-11       Impact factor: 5.063

Review 5.  A risk-benefit assessment of aprotinin in cardiac surgical procedures.

Authors:  W B Dobkowski; J M Murkin
Journal:  Drug Saf       Date:  1998-01       Impact factor: 5.606

Review 6.  Antifibrinolytic therapy in cardiac surgery.

Authors:  R H Chen; O H Frazier; D A Cooley
Journal:  Tex Heart Inst J       Date:  1995

Review 7.  Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery.

Authors:  R Davis; R Whittington
Journal:  Drugs       Date:  1995-06       Impact factor: 9.546

8.  A Comparative Study to Determine the Effect of Intravenous Magnesium on Postoperative Bleeding after on Pump CABG in Patients Receiving Pre-Operative Aspirin.

Authors:  Sampa Dutta Gupta; Soumendu Pal; Anupam Goswami; Sandip Bhadra; Sripurna Mandal; Chandashi Naskar; Sudakshina Mukherjee; Debasish Boral
Journal:  Indian J Anaesth       Date:  2009-04

Review 9.  Pharmacological approaches to reduce perioperative transfusion requirements in the aged.

Authors:  T Tasaki; H Ohto; R Motoki
Journal:  Drugs Aging       Date:  1995-02       Impact factor: 3.923

Review 10.  Natural and synthetic antifibrinolytics in cardiac surgery.

Authors:  J F Hardy; J Desroches
Journal:  Can J Anaesth       Date:  1992-04       Impact factor: 5.063

  10 in total

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