Juan Marco Figueira Gonçalves1, Miguel Ángel García Bello2, Rafael Golpe3, Juan Luis Alonso Jerez4, Ignacio García-Talavera1. 1. Pneumology and Thoracic Surgery Service, University Hospital Nuestra Señora de la Candelaria (HUNSC), Santa Cruz de Tenerife, Spain. 2. Division of Clinical Epidemiology and Biostatistics, Research Unit, University Hospital Nuestra Señora de la Candelaria (HUNSC) and Primary Care Management, Santa Cruz de Tenerife, Spain. 3. Respiratory Medicine Service, University Hospital Lucus Augusti, Lugo, Spain. 4. General Practice, C.S Tejina, Servicio Canario de Salud, Santa Cruz de Tenerife, Spain.
Abstract
INTRODUCTION: Suffering type 2 diabetes mellitus (T2DM) appears to promote the occurrence of respiratory infections. However, studies to evaluate the risk of hospital admission due to exacerbations in patients with chronic obstructive pulmonary disease (COPD) and concomitant T2DM are scarce. MATERIALS AND METHODS: Prospective, observational study with a maximum follow-up of 18 months. Information on lung function, body mass index, degree of dyspnea, number of exacerbations, comorbidities and pneumococcal vaccination was obtained. Patients were classified into the categories COPD with (COPD/+T2DM) and without T2DM (COPD/-T2DM). RESULTS: A total of 121 patients with COPD were enrolled. Forty-seven (38%) of the study participants were diabetic. The presence of T2DM increased the risk of hospital admission due to COPD exacerbation (OR 2.66; P = 0.031), but no significant difference in the total number of exacerbations was detected. CONCLUSIONS: The risk of hospital admission in the course of exacerbation seems to be higher in COPD/+T2DM patients than in COPD/-T2DM subjects.
INTRODUCTION: Suffering type 2 diabetes mellitus (T2DM) appears to promote the occurrence of respiratory infections. However, studies to evaluate the risk of hospital admission due to exacerbations in patients with chronic obstructive pulmonary disease (COPD) and concomitant T2DM are scarce. MATERIALS AND METHODS: Prospective, observational study with a maximum follow-up of 18 months. Information on lung function, body mass index, degree of dyspnea, number of exacerbations, comorbidities and pneumococcal vaccination was obtained. Patients were classified into the categories COPD with (COPD/+T2DM) and without T2DM (COPD/-T2DM). RESULTS: A total of 121 patients with COPD were enrolled. Forty-seven (38%) of the study participants were diabetic. The presence of T2DM increased the risk of hospital admission due to COPD exacerbation (OR 2.66; P = 0.031), but no significant difference in the total number of exacerbations was detected. CONCLUSIONS: The risk of hospital admission in the course of exacerbation seems to be higher in COPD/+T2DM patients than in COPD/-T2DM subjects.
Authors: Spyridon Fortis; Alejandro P Comellas; Surya P Bhatt; Eric A Hoffman; MeiLan K Han; Nirav R Bhakta; Robert Paine; Bonnie Ronish; Richard E Kanner; Mark Dransfield; Daniel Hoesterey; Russell G Buhr; R Graham Barr; Brett Dolezal; Victor E Ortega; M Bradley Drummond; Mehrdad Arjomandi; Robert J Kaner; Victor Kim; Jeffrey L Curtis; Russell P Bowler; Fernando Martinez; Wassim W Labaki; Christopher B Cooper; Wanda K O'Neal; Gerald Criner; Nadia N Hansel; Jerry A Krishnan; Prescott Woodruff; David Couper; Donald Tashkin; Igor Barjaktarevic Journal: Chest Date: 2021-02-01 Impact factor: 10.262
Authors: Juan Marco Figueira-Gonçalves; José María Hernández-Pérez; Carlos Cabrera-López; Aurelio Luis Wangüemert-Pérez; Ignacio García-Talavera; Yolanda Ramallo-Fariña; Carolina Ramos-Izquierdo; Luis Manuel González-García; Sara Guanche-Dorta Journal: BMC Res Notes Date: 2022-02-10