Literature DB >> 32781041

Microenvironment-Mediated Resistance to Anti-Androgen Therapy.

Jacob J Orme1, Haojie Huang2.   

Abstract

In this issue of Cancer Cell, Zhang et al. expose new possibilities for targeting castration-resistant prostate cancer (CRPC). Activation of the HER2/HER3 axis by cancer-associated fibroblast-secreted NRG1 mediates castration resistance, recommending novel applications of clinical anti-NRG1/HER3 therapeutics in treating CRPC.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Year:  2020        PMID： 32781041     DOI： 10.1016/j.ccell.2020.07.007

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  3 in total

1.  Re-Clustering and Profiling of Digestive System Tumors According to Microenvironment Components.

Authors:  Yongwei Wang; Sen Guo; Zhihong Chen; Bing Bai; Shuo Wang; Yaxian Gao
Journal:  Front Oncol       Date:  2021-02-10       Impact factor: 6.244

2.  Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis.

Authors:  Hyunho Han; Yan Wang; Josue Curto; Sreeharsha Gurrapu; Sara Laudato; Alekya Rumandla; Goutam Chakraborty; Xiaobo Wang; Hong Chen; Yan Jiang; Dhiraj Kumar; Emily G Caggiano; Monica Capogiri; Boyu Zhang; Yan Ji; Sankar N Maity; Min Hu; Shanshan Bai; Ana M Aparicio; Eleni Efstathiou; Christopher J Logothetis; Nicholas Navin; Nora M Navone; Yu Chen; Filippo G Giancotti
Journal:  Cell Rep       Date:  2022-04-05       Impact factor: 9.995

Review 3.  Drug resistance in metastatic castration-resistant prostate cancer: an update on the status quo.

Authors:  Amani Yehya; Fatima Ghamlouche; Amin Zahwe; Yousef Zeid; Kevork Wakimian; Deborah Mukherji; Wassim Abou-Kheir
Journal:  Cancer Drug Resist       Date:  2022-06-22
  3 in total

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