Disinhibition and Detachment in Adolescence: A Developmental Cognitive Neuroscience Perspective on the Alternative Model for Personality Disorders.

Personality pathology often emerges during adolescence, but attempts to understand its neurocognitive basis have traditionally been undermined by problems associated with the categorical classification of personality disorders. In contrast, dimensional models of personality pathology, such as the Alternative Model for Personality Disorders (AMPD) in DSM-5, may provide a stronger foundation for neurobiological investigations of maladaptive individual differences in personality. As an example, we review studies of the adolescent development of reward processing and cognitive control and connect these systems to the normal personality hierarchy and to two dimensions included in the AMPD - Detachment and Disinhibition. We argue that by linking developmental changes in these systems to the AMPD, researchers will be better positioned to understand the relationship between neurocognitive development and the expression of personality pathology in adolescence and early adulthood.