Literature DB >> 3277664

A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure.

G R Duff1, P A Graham.   

Abstract

The effect of topical carteolol 2% on the intraocular pressures of 12 patients suspected of having glaucoma was measured in a double-crossover trial of six weeks' duration. Carteolol produced a significant reduction in intraocular pressure (p less than or equal to 0.001), when compared with placebo. This represented reductions of 11% and 14%, after one and two weeks of treatment.

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Year:  1988        PMID： 3277664      PMCID： PMC1041361          DOI： 10.1136/bjo.72.1.27

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN： 0007-1161            Impact factor:   4.638


  4 in total

1.  Selective perimetry for glaucomatous defects in ocular hypertension.

Authors:  M F Armaly
Journal:  Arch Ophthalmol       Date:  1972-05

2.  [Effects of beta-blocking agent carteolol on healthy volunteers and glaucoma patients (author's transl)].

Authors:  C Negishi; S Ueda; A Kanai; A Nakajima; M Funahashi; Y Kitazawa; S Komemushi
Journal:  Nippon Ganka Gakkai Zasshi       Date:  1981-01

3.  The two-period cross-over clinical trial.

Authors:  M Hills; P Armitage
Journal:  Br J Clin Pharmacol       Date:  1979-07       Impact factor: 4.335

4.  [Ocular hypotensive effects of carteolol hydrochloride in primary open-angle glaucoma and ocular hypertensive patients. A double-masked cross-over study for the determination of concentrations optimal for the clinical use (author's transl)].

Authors:  Y Kitazawa; I Azuma; M Takase; S Komemushi
Journal:  Nippon Ganka Gakkai Zasshi       Date:  1981
  4 in total
  3 in total

1.  The 12-hour control of intraocular pressure on carteolol 2% twice daily.

Authors:  G R Duff; R G Newcombe
Journal:  Br J Ophthalmol       Date:  1988-12       Impact factor: 4.638

Review 2.  Ocular carteolol. A review of its pharmacological properties, and therapeutic use in glaucoma and ocular hypertension.

Authors:  P Chrisp; E M Sorkin
Journal:  Drugs Aging       Date:  1992 Jan-Feb       Impact factor: 3.923

Review 3.  Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects.

Authors:  A M Brooks; W E Gillies
Journal:  Drugs Aging       Date:  1992 May-Jun       Impact factor: 3.923
  3 in total

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