Literature DB >> 3277629

Insulin action on brain microvessels; effect on alkaline phosphatase.

R E Catalán1, A M Martínez, M D Aragonés, B G Miguel, A Robles.   

Abstract

The effects of insulin on brain alkaline phosphatase activity have been examined. Insulin inhibited the activity of alkaline phosphatase on brain microvessels in in vitro experiments. The inhibition observed was of the non-competitive type. These observations indicate that the hormone is able to induce neurochemical modifications revealed in this case as changes in the phosphate transfer enzymes in brain microvessels.

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Year:  1988        PMID： 3277629     DOI： 10.1016/0006-291x(88)90433-0

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


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