Ananda S Bandyopadhyay1, Grace R Macklin2. 1. Bill & Melinda Gates Foundation, Seattle, Washington, USA. 2. London School of Hygiene and Tropical Medicine, London, UK.
Abstract
PURPOSE OF REVIEW: Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS: An upsurge in wild poliovirus type 1 cases in Pakistan and Afghanistan and an expansion of type 2 circulating vaccine-derived poliovirus transmission in multiple countries threaten the remarkable progress made over past several decades by the global eradication program. These challenges have also spurred innovation on multiple fronts, including earlier detection, enhanced environmental surveillance and safer and more affordable vaccine options. SUMMARY: A concerted effort to adapt program strategies to address context-specific challenges and continued focus on innovations to enhance detection and response capabilities will be the key to achieve and sustain eradication of all types of polioviruses.
PURPOSE OF REVIEW: Focusing on the key developments since January 2019, this review aims to inform policymakers and clinical practitioners on the latest on evolving global polio epidemiology and scientific advancements to guide strategies for eradication. RECENT FINDINGS: An upsurge in wild poliovirus type 1 cases in Pakistan and Afghanistan and an expansion of type 2 circulating vaccine-derived poliovirus transmission in multiple countries threaten the remarkable progress made over past several decades by the global eradication program. These challenges have also spurred innovation on multiple fronts, including earlier detection, enhanced environmental surveillance and safer and more affordable vaccine options. SUMMARY: A concerted effort to adapt program strategies to address context-specific challenges and continued focus on innovations to enhance detection and response capabilities will be the key to achieve and sustain eradication of all types of polioviruses.
Authors: Ethel D Weld; Jacqueline Astemborski; Gregory D Kirk; Mark S Sulkowski; Stephanie Katz; Richard Rothman; Sunil S Solomon; Gail V Matthews; Yu Hsiang Hsieh; Malvika Verma; Giovanni Traverso; Susan Swindells; Andrew Owen; Jordan Feld; Charles Flexner; Shruti H Mehta; David L Thomas Journal: Clin Infect Dis Date: 2022-08-24 Impact factor: 20.999