Literature DB >> 32767920

The Plausible Role of Indian Traditional Medicine in Combating Corona Virus (SARS-CoV 2): A Mini-Review.

J Adithya1, Bhagyalakshmi Nair1, T S Aishwarya1, Lekshmi R Nath1.   

Abstract

SARS-CoV 2 is a novel virus strain of Coronavirus, reported in China in late December 2019. Its highly contagious nature in humans has prompted WHO to designate the ongoing pandemic as a Public Health Emergency of International Concern. At this moment, there is no specific treatment and the therapeutic strategies to deal with the infection are only supportive, with prevention aimed at reducing community transmission. A permanent solution for the pandemic, which has brought the world economy to the edge of collapse, is the need of the hour. This situation has brought intense research in traditional systems of medicine. Indian Traditional System, Ayurveda, has a clear concept of the cause and treatment of pandemics. Through this review, information on the potential antiviral traditional medicines along with their immunomodulatory pathways are discussed. We have covered the seven most important Indian traditional plants with antiviral properties: Withania somnifera (L.) Dunal (family: Solanaceae), Tinospora cordifolia (Thunb.) Miers (family: Menispermaceae), Phyllanthus emblica L. (family: Euphorbiaceae), Asparagus racemosus L. (family: Liliaceae), Glycyrrhiza glabra L. (family: Fabaceae), Ocimum sanctum L. (family: Lamiaceae) and Azadirachta indica A. Juss (family: Meliaceae) in this review. An attempt is also made to bring into limelight the importance of dietary polyphenol, Quercetin, which is a potential drug candidate in the making against the SARS-CoV2 virus. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Keywords:  COVID 19; SARS-CoV2 virus; ayurveda; phytochemical; quercetin; traditional medicine

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Year:  2021        PMID: 32767920     DOI: 10.2174/1389201021666200807111359

Source DB:  PubMed          Journal:  Curr Pharm Biotechnol        ISSN: 1389-2010            Impact factor:   2.837


  5 in total

Review 1.  The Antimicrobial Potential of the Neem Tree Azadirachta indica.

Authors:  Marina R Wylie; D Scott Merrell
Journal:  Front Pharmacol       Date:  2022-05-30       Impact factor: 5.988

Review 2.  Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic insight.

Authors:  Dheeraj Bisht; Mohmmad Rashid; Rajeshwar Kamal Kant Arya; Deepak Kumar; Sushil Kumar Chaudhary; Vijay Singh Rana; Neeraj K Sethiya
Journal:  Phytomed Plus       Date:  2021-12-18

3.  Evaluation of the active constituents of Nilavembu Kudineer for viral replication inhibition against SARS-CoV-2: An approach to targeting RNA-dependent RNA polymerase (RdRp).

Authors:  Anisha Kuriakose; Bhagyalakshmi Nair; Mohamed A Abdelgawad; Adeniyi T Adewum; Mahmoud E S Soliman; Bijo Mathew; Lekshmi R Nath
Journal:  J Food Biochem       Date:  2022-08-22       Impact factor: 3.654

Review 4.  Dietary foods containing nitric oxide donors can be early curators of SARS-CoV-2 infection: A possible role in the immune system.

Authors:  S Swathi Krishna; Arumugam Thennavan; S K Kanthlal
Journal:  J Food Biochem       Date:  2021-08-09       Impact factor: 3.654

5.  Identification of Papain-Like Protease inhibitors of SARS CoV-2 through HTVS, Molecular docking, MMGBSA and Molecular dynamics approach.

Authors:  Srikanth Jupudi; Kalirajan Rajagopal; Sankaranarayanan Murugesan; Banoth Karan Kumar; Kannan Raman; Gowramma Byran; Jayakuamar Chennaiah; Velayutham Pillai Muthiah; Bharathi Dasan P; Sathianarayanan Sankaran
Journal:  S Afr J Bot       Date:  2021-12-03       Impact factor: 2.315

  5 in total

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