Maria Nattestad1, Robert Aboukhalil2, Chen-Shan Chin3, Michael C Schatz1,4,5. 1. Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA. 2. Invitae, San Francisco, CA 94103, USA. 3. DNAnexus, Mountain View, CA 94040, USA. 4. Department of Computer Science, Johns Hopkins University, Baltimore, MD 21218, USA. 5. Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.
Abstract
SUMMARY: Ribbon is an alignment visualization tool that shows how alignments are positioned within both the reference and read contexts, giving an intuitive view that enables a better understanding of structural variants and the read evidence supporting them. Ribbon was born out of a need to curate complex structural variant calls and determine whether each was well supported by long-read evidence, and it uses the same intuitive visualization method to shed light on contig alignments from genome-to-genome comparisons. AVAILABILITY AND IMPLEMENTATION: Ribbon is freely available online at http://genomeribbon.com/ and is open-source at https://github.com/marianattestad/ribbon. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
SUMMARY: Ribbon is an alignment visualization tool that shows how alignments are positioned within both the reference and read contexts, giving an intuitive view that enables a better understanding of structural variants and the read evidence supporting them. Ribbon was born out of a need to curate complex structural variant calls and determine whether each was well supported by long-read evidence, and it uses the same intuitive visualization method to shed light on contig alignments from genome-to-genome comparisons. AVAILABILITY AND IMPLEMENTATION: Ribbon is freely available online at http://genomeribbon.com/ and is open-source at https://github.com/marianattestad/ribbon. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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