Anna Turusheva1, Elena Frolova1, Yulia Kotovskaya2, Yurij Petrosyan1, Rauli Dumbadze1. 1. The North-Western State Medical University Named After I.I. Mechnikov, St. Petersburg, Russia. 2. Russian Clinical and Research Center of Gerontology, Pirogov Russian National Research Medical University, Moscow, Russia.
Abstract
PURPOSE: This study was conducted to investigate the relationships between arterial stiffness, frailty and fall-related injuries among community-dwelling older adults. MATERIALS AND METHODS: A cross-sectional study of a random sample of older adults aged 60 years and older was conducted. Main study parameters: arterial stiffness was measured by the determining the cardio-ankle vascular index (CAVI); Frailty status was defined using a 7-item frailty screening scale, developed in Russia. This questionnaire included question about falls and fall-related injuries. Orthostatic test and anthropometric tests were done. Medical history (comorbidity, medications), the Osteoporosis Self-assessment Tool (OST), nutritional, physical, cognitive and functional status were evaluated. RESULTS: The study population included 163 people aged 60-89 years. The average predicted value of CAVI in women aged 60-69 was 9.13 ± 0.13, in men, 9.49 ± 0.05; in women aged 70-79, it was 9.49 ± 0.16, in men, 9.73 ±0.11; in women aged 80 and older it was 10.04 ±0.18, in men, 10.24 ±0.10 units. The CAVI above the predicted value was associated with fall-related injuries even after adjustment for age, sex, use of β-blockers (BBs), history of stroke, and region of residence with the odds ratio 3.52 (95% CI: 1.03 -12.04). CONCLUSION: Our study revealed an independent association between arterial stiffness and fall-related injuries in older adults over 60 years. The findings suggest that clinicians, especially geriatricians, should pay attention to arterial stiffness of patients with fall-related injuries. Similarly, the patients with CAVI above age-predicted value should be evaluated for risk of falls for prevention of fall-related injuries.
PURPOSE: This study was conducted to investigate the relationships between arterial stiffness, frailty and fall-related injuries among community-dwelling older adults. MATERIALS AND METHODS: A cross-sectional study of a random sample of older adults aged 60 years and older was conducted. Main study parameters: arterial stiffness was measured by the determining the cardio-ankle vascular index (CAVI); Frailty status was defined using a 7-item frailty screening scale, developed in Russia. This questionnaire included question about falls and fall-related injuries. Orthostatic test and anthropometric tests were done. Medical history (comorbidity, medications), the Osteoporosis Self-assessment Tool (OST), nutritional, physical, cognitive and functional status were evaluated. RESULTS: The study population included 163 people aged 60-89 years. The average predicted value of CAVI in women aged 60-69 was 9.13 ± 0.13, in men, 9.49 ± 0.05; in women aged 70-79, it was 9.49 ± 0.16, in men, 9.73 ±0.11; in women aged 80 and older it was 10.04 ±0.18, in men, 10.24 ±0.10 units. The CAVI above the predicted value was associated with fall-related injuries even after adjustment for age, sex, use of β-blockers (BBs), history of stroke, and region of residence with the odds ratio 3.52 (95% CI: 1.03 -12.04). CONCLUSION: Our study revealed an independent association between arterial stiffness and fall-related injuries in older adults over 60 years. The findings suggest that clinicians, especially geriatricians, should pay attention to arterial stiffness of patients with fall-related injuries. Similarly, the patients with CAVI above age-predicted value should be evaluated for risk of falls for prevention of fall-related injuries.
Authors: Jaromira Gajdova; David Karasek; Dominika Goldmannova; Ondrej Krystynik; Jan Schovanek; Helena Vaverkova; Josef Zadrazil Journal: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Date: 2017-06-05 Impact factor: 1.245
Authors: Ariela R Orkaby; Kathryn L Lunetta; Fangui J Sun; Jane A Driver; Emelia J Benjamin; Naomi M Hamburg; Gary F Mitchell; Ramachandran S Vasan; Joanne M Murabito Journal: J Gerontol A Biol Sci Med Sci Date: 2019-02-15 Impact factor: 6.053
Authors: Jirar Topouchian; Carlos Labat; Sylvie Gautier; Magnus Bäck; Apostolos Achimastos; Jacques Blacher; Marcin Cwynar; Alejandro de la Sierra; Denes Pall; Francesco Fantin; Katalin Farkas; Luis Garcia-Ortiz; Zoya Hakobyan; Piotr Jankowski; Ana Jelakovic; Zhanna Kobalava; Alexandra Konradi; Yulia Kotovskaya; Marina Kotsani; Irina Lazareva; Alexander Litvin; Viktor Milyagin; Iveta Mintale; Oscar Persson; Rafael Ramos; Anatoly Rogoza; Ligita Ryliskyte; Angelo Scuteri; Yuriy Sirenko; Georges Soulis; Nebojsa Tasic; Maryna Udovychenko; Saule Urazalina; Peter Wohlfahrt; Parounak Zelveian; Athanase Benetos; Roland Asmar Journal: J Hypertens Date: 2018-04 Impact factor: 4.844