Literature DB >> 3276378

The irritable bowel syndrome.

S M Collins1.   

Abstract

The irritable bowel syndrome (IBS) is an extremely common disorder. It is believed to occur usually after emotional stress and perhaps because of behavioural and dietary factors. There is definite evidence of disturbed gastrointestinal function associated with IBS; however, a diagnostic marker remains elusive. The current trend is to diagnose IBS on the basis of the patient's history and the findings at physical examination and after minimal investigation. The physician-patient relationship remains the most important factor in the management of IBS. Long-term benefit may be achieved with the use of dietary fibre supplements or stool-bulking agents. The evaluation of currently available drugs is difficult because of the placebo effect. Drug therapy should be aimed at specific symptoms and used mainly during the initial phase of treatment.

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Year:  1988        PMID: 3276378      PMCID: PMC1267619     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  78 in total

1.  Effect of cholecystokinin on colonic motility and symptoms in patients with the irritable-bowel syndrome.

Authors:  R F Harvey; A E Read
Journal:  Lancet       Date:  1973-01-06       Impact factor: 79.321

2.  Prognosis in the irritable-bowel syndrome. A prospective study.

Authors:  S L Waller; J J Misiewicz
Journal:  Lancet       Date:  1969-10-11       Impact factor: 79.321

3.  Psychological significance of the irritable colon syndrome.

Authors:  I G Hislop
Journal:  Gut       Date:  1971-06       Impact factor: 23.059

Review 4.  Colonic myoelectric activity in the irritable bowel syndrome.

Authors:  W J Snape; G M Carlson; S Cohen
Journal:  Gastroenterology       Date:  1976-03       Impact factor: 22.682

5.  A secretory epithelium of the small intestine with increased sensitivity to bile acids in irritable bowel syndrome associated with diarrhoea.

Authors:  E Oddsson; J Rask-Madsen; E Krag
Journal:  Scand J Gastroenterol       Date:  1978       Impact factor: 2.423

6.  Effects of intravenous and oral domperidone on the motor function of the stomach and small intestine.

Authors:  R Baeyens; E van de Velde; A De Schepper; F Wollaert; A Reyntjens
Journal:  Postgrad Med J       Date:  1979       Impact factor: 2.401

7.  Psyllium therapy in the irritable bowel syndrome. A double-blind trial.

Authors:  G F Longstreth; D D Fox; L Youkeles; A B Forsythe; D A Wolochow
Journal:  Ann Intern Med       Date:  1981-07       Impact factor: 25.391

8.  Learned illness behavior in patients with irritable bowel syndrome and peptic ulcer.

Authors:  W E Whitehead; C Winget; A S Fedoravicius; S Wooley; B Blackwell
Journal:  Dig Dis Sci       Date:  1982-03       Impact factor: 3.199

9.  Electrogastrographic study of patients with unexplained nausea, bloating, and vomiting.

Authors:  C H You; K Y Lee; W Y Chey; R Menguy
Journal:  Gastroenterology       Date:  1980-08       Impact factor: 22.682

10.  Wheat fibre and irritable bowel syndrome. A controlled trial.

Authors:  A P Manning; K W Heaton; R F Harvey
Journal:  Lancet       Date:  1977-08-27       Impact factor: 79.321

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  1 in total

Review 1.  The extracolonic manifestations of the irritable bowel syndrome.

Authors:  K Tilbe; S Sullivan
Journal:  CMAJ       Date:  1990-03-15       Impact factor: 8.262

  1 in total

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