Literature DB >> 32763186

Microbial RNAs Pressure Piezo1 to Respond.

Juan D Matute1, Jinzhi Duan2, Richard S Blumberg3.   

Abstract

Serotonin production by enterochromaffin cells (ECs) is microbiota-dependent, but the mechanism of this is unknown. In this issue of Cell, Sugisawa et al. demonstrate that Piezo1 in ECs senses single-strand RNA (ssRNA) from intestinal microbiota to promote serotonin production. Deletion of Piezo1 in intestinal epithelium promotes bone formation, decreases peristalsis, and protects from colitis because of decreased serotonin.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Year:  2020        PMID： 32763186      PMCID： PMC7880614          DOI： 10.1016/j.cell.2020.07.015

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  11 in total

1.  Tissue 5-hydroxytryptamine and urinary 5-hydroxyindoleacetic acid after partial or total removal of the gastro-intestinal tract in the rat.

Authors:  G Bertaccini
Journal:  J Physiol       Date:  1960-09       Impact factor: 5.182

2.  Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping.

Authors:  Helmuth Gehart; Johan H van Es; Karien Hamer; Joep Beumer; Kai Kretzschmar; Johanna F Dekkers; Anne Rios; Hans Clevers
Journal:  Cell       Date:  2019-01-31       Impact factor: 41.582

3.  RNA Sensing by Gut Piezo1 Is Essential for Systemic Serotonin Synthesis.

Authors:  Erika Sugisawa; Yasunori Takayama; Naoki Takemura; Takeshi Kondo; Shigetsugu Hatakeyama; Yutaro Kumagai; Masataka Sunagawa; Makoto Tominaga; Kenta Maruyama
Journal:  Cell       Date:  2020-07-07       Impact factor: 41.582

Review 4.  Non-conventional features of peripheral serotonin signalling - the gut and beyond.

Authors:  Stephanie N Spohn; Gary M Mawe
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-05-10       Impact factor: 46.802

5.  Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.

Authors:  Bertrand Coste; Jayanti Mathur; Manuela Schmidt; Taryn J Earley; Sanjeev Ranade; Matt J Petrus; Adrienne E Dubin; Ardem Patapoutian
Journal:  Science       Date:  2010-09-02       Impact factor: 47.728

6.  Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update From the American College of Physicians.

Authors:  Amir Qaseem; Mary Ann Forciea; Robert M McLean; Thomas D Denberg; Michael J Barry; Molly Cooke; Nick Fitterman; Russell P Harris; Linda L Humphrey; Devan Kansagara; Robert M McLean; Tanveer P Mir; Holger J Schünemann
Journal:  Ann Intern Med       Date:  2017-05-09       Impact factor: 25.391

7.  Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.

Authors:  Jessica M Yano; Kristie Yu; Gregory P Donaldson; Gauri G Shastri; Phoebe Ann; Liang Ma; Cathryn R Nagler; Rustem F Ismagilov; Sarkis K Mazmanian; Elaine Y Hsiao
Journal:  Cell       Date:  2015-04-09       Impact factor: 41.582

8.  Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.

Authors:  Vijay K Yadav; Je-Hwang Ryu; Nina Suda; Kenji F Tanaka; Jay A Gingrich; Günther Schütz; Francis H Glorieux; Cherie Y Chiang; Jeffrey D Zajac; Karl L Insogna; J John Mann; Rene Hen; Patricia Ducy; Gerard Karsenty
Journal:  Cell       Date:  2008-11-28       Impact factor: 41.582

Review 9.  Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

Authors:  Maria T Abreu
Journal:  Nat Rev Immunol       Date:  2010-02       Impact factor: 53.106

10.  A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release.

Authors:  Constanza Alcaino; Kaitlyn R Knutson; Anthony J Treichel; Gulcan Yildiz; Peter R Strege; David R Linden; Joyce H Li; Andrew B Leiter; Joseph H Szurszewski; Gianrico Farrugia; Arthur Beyder
Journal:  Proc Natl Acad Sci U S A       Date:  2018-07-23       Impact factor: 11.205
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  3 in total

Review 1.  Potential Roles of Enterochromaffin Cells in Early Life Stress-Induced Irritable Bowel Syndrome.

Authors:  Enfu Tao; Zhenya Zhu; Chenmin Hu; Gao Long; Bo Chen; Rui Guo; Marong Fang; Mizu Jiang
Journal:  Front Cell Neurosci       Date:  2022-03-15       Impact factor: 5.505

Review 2.  Cancer predictive studies.

Authors:  Ivano Amelio; Riccardo Bertolo; Pierluigi Bove; Eleonora Candi; Marcello Chiocchi; Chiara Cipriani; Nicola Di Daniele; Carlo Ganini; Hartmut Juhl; Alessandro Mauriello; Carla Marani; John Marshall; Manuela Montanaro; Giampiero Palmieri; Mauro Piacentini; Giuseppe Sica; Manfredi Tesauro; Valentina Rovella; Giuseppe Tisone; Yufang Shi; Ying Wang; Gerry Melino
Journal:  Biol Direct       Date:  2020-10-14       Impact factor: 4.540

3.  Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats.

Authors:  Yuanhang Wu; Jianlin Wu; Zhikun Lin; Qian Wang; Ying Li; Aman Wang; Xiu Shan; Jiwei Liu
Journal:  J Immunol Res       Date:  2021-09-14       Impact factor: 4.818
  3 in total

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