| Literature DB >> 3275629 |
R E Roberts1, C I Lienhard, C G Gaines, J M Smith, J R Guest.
Abstract
The guaC (GMP reductase), nadC (quinolinate phosphoribosyltransferase), and aroP (aromatic amino acid permease) genes of Escherichia coli K-12 were located in the 2.5-min region of the chromosome (muT-guaC-nadC-aroP-aceE) by a combination of linkage analysis, deletion mapping, restriction analysis, and plasmid subcloning. The guaC locus expressed a product of Mr 37,000 with a clockwise transcriptional polarity, and the GMP reductase activities of guaC+ plasmid-containing strains were amplified 15- to 20-fold.Entities:
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Year: 1988 PMID: 3275629 PMCID: PMC210669 DOI: 10.1128/jb.170.1.463-467.1988
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490