| Literature DB >> 32755606 |
Nabil E Boutagy1, Joseph W Fowler1, William C Sessa2.
Abstract
The precise mechanisms of free fatty acid (FFA) uptake in the vascular endothelium are unclear. In this issue of Cell Metabolism, Ibrahim et al. (2020) discover that FFA uptake is partially mediated by a vectorial, ER-mitochondria link, in which mitochondrial ATP production is locally used for the acyl-CoA synthetase activity of the ER-located fatty acid transport protein 4.Entities:
Mesh:
Substances:
Year: 2020 PMID: 32755606 PMCID: PMC7652390 DOI: 10.1016/j.cmet.2020.07.010
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287