Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cell Biology: Social Distancing of Microtubule Ends Increases Their Assembly Rates.

Literature DB >> 32750351

Cell Biology: Social Distancing of Microtubule Ends Increases Their Assembly Rates.

Abstract

Microtubules assembled from artificial centrosomes in microfluidic chambers of defined size are amenable to high resolution live imaging of their dynamics and space-filling properties. By using this experimental regime in conjunction with cytoplasmic extract, a new study finds that microtubule end density negatively influences their assembly rates.

Entities: Chemical Disease Gene Species

Year: 2020 PMID： 32750351 PMCID： PMC7553204 DOI： 10.1016/j.cub.2020.06.014

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

Keyword Cloud
References

18 in total

1. Fabrication of Functional Biomaterial Microstructures by in Situ Photopolymerization and Photodegradation.

Authors: Paige J LeValley; Ben Noren; Prathamesh M Kharkar; April M Kloxin; Jesse C Gatlin; John S Oakey
Journal: ACS Biomater Sci Eng Date: 2018-07-05

2. Estimation of the diffusion-limited rate of microtubule assembly.

Authors: D J Odde
Journal: Biophys J Date: 1997-07 Impact factor: 4.033

3. Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo.

Authors: Martin Srayko; Aynur Kaya; Joanne Stamford; Anthony A Hyman
Journal: Dev Cell Date: 2005-08 Impact factor: 12.270

10. Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene (TOG) domain arrays.

Authors: Stanley Nithianantham; Brian D Cook; Madeleine Beans; Fei Guo; Fred Chang; Jawdat Al-Bassam
Journal: Elife Date: 2018-11-13 Impact factor: 8.140

Cell Biology: Social Distancing of Microtubule Ends Increases Their Assembly Rates.

1. Fabrication of Functional Biomaterial Microstructures by in Situ Photopolymerization and Photodegradation.

2. Estimation of the diffusion-limited rate of microtubule assembly.

3. Identification and characterization of factors required for microtubule growth and nucleation in the early C. elegans embryo.

4. Light-inducible activation of cell cycle progression in Xenopus egg extracts under microfluidic confinement.

5. Changes in cytoplasmic volume are sufficient to drive spindle scaling.

Review 6. Biological Scaling Problems and Solutions in Amphibians.

7. Microtubule Growth Rates Are Sensitive to Global and Local Changes in Microtubule Plus-End Density.

8. Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins.

9. Physical basis of large microtubule aster growth.

10. Structural basis of tubulin recruitment and assembly by microtubule polymerases with tumor overexpressed gene (TOG) domain arrays.