| Literature DB >> 32748132 |
Z D Zhuravleva1, M A Mogutina2, I V Mukhina2,3, M Ya Druzin4.
Abstract
We studied the effect of bilateral microinjections of selective pharmacological agents modulating glycine receptor activity into the medial preoptic nucleus on sexual behavior of male Wistar rats. Application of the glycine receptor blocker strychnine (20 μM, 2 μl) led to a significant inhibition of both appetitive and consummatory components of sexual behavior, whereas stimulation with glycine (1 mM and 50 μM, 2 μl) had no significant effect.Entities:
Keywords: glycine receptors; hypothalamus; sexual behavior
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Year: 2020 PMID： 32748132 DOI： 10.1007/s10517-020-04873-y
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804