Literature DB >> 32745690

Preoperative hypoalbuminemia: Poor functional outcomes and quality of life after hip fracture surgery.

Shaoen David Sim1, Yilin Eileen Sim2, Kenny Tay2, Tet Sen Howe2, Meng Ai Png2, Chee Cheng Paul Chang2, Hairil Rizal Abdullah2, Joyce Suang Bee Koh2.   

Abstract

AIMS: Hip fracture patients have severe deterioration of their quality of life and function after their injury. Markers of malnutrition such as low albumin and low body mass index (BMI) have been shown to increase mortality and complication rates but their effect on recovery of quality of life and function after hip fracture surgery is unclear. The main aim of this paper is to further investigate if low albumin affects recovery after hip fracture surgery, while additionally studying low BMI as a possible risk factor for poor recovery. PATIENTS AND METHODS: Retrospective analysis of 971 patients who underwent surgery for fragility hip fractures between January 2012 and December 2016 was performed. Demographic data, preoperative serum albumin and haemoglobin levels, BMI, Charlson Comorbidity Index (CCI), type of surgery (fixation vs replacement) and site of surgery were obtained. Patients were assessed using the Parker Mobility Scale (PMS), Harris Hip Score(HHS), Medical Outcomes Study 36-item Short-Form Health Survey (SF36) at pre-fracture, 6 weeks and 6 months after surgery. HHS was not available pre-operatively. Patients were grouped according to their albumin levels (low ≤35 g/L or normal) and BMI (underweight <18.5 or normal). Univariate and multivariate analyses were performed to examine the association between albumin and BMI and 6-month scores.
RESULTS: On univariate analysis, patients with low albumin ≤35 g/L had lower baseline PMS and SF36 Physical Functioning (PF) score. On multivariate analysis, preoperative hypoalbuminemia was associated with lower 6-month HHS, PMS and SF36 PF scores even after accounting for baseline scores and other confounders. BMI had no effect on 6-month scores.
CONCLUSION: Low albumin (≤35 g/L) is prevalent in elderly hip fracture patients and is associated with slower recovery of function and quality of life after surgery. Low albumin can be a useful prognostic tool to identify patients with poor recovery for further intervention or rehabilitation after hip fracture surgery.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Albumin; Functional recovery; Hip fracture; Osteoporosis

Mesh:

Year:  2020        PMID: 32745690     DOI: 10.1016/j.bone.2020.115567

Source DB:  PubMed          Journal:  Bone        ISSN: 1873-2763            Impact factor:   4.398


  5 in total

1.  Higher Charlson Comorbidity Index Increases 90-Day Readmission Rate with Poorer Functional Outcomes in Surgically Treated Hip Fracture Patients.

Authors:  Cheryl Gatot; Evan Shern-En Tan; Ming Han Lincoln Liow; Jerry Yongqiang Chen; Meng Ai Png; Mann Hong Tan; Tet Sen Howe; Joyce Suang Bee Koh
Journal:  Geriatr Orthop Surg Rehabil       Date:  2021-08-13

2.  A Prediction Modeling Based on the Hospital for Special Surgery (HSS) Knee Score for Poor Postoperative Functional Prognosis of Elderly Patients with Patellar Fractures.

Authors:  Chenting Ying; Chenyang Guo; Zhenlin Wang; Yiming Chen; Jiahui Sun; Xin Qi; Yisheng Chen; Jie Tao
Journal:  Biomed Res Int       Date:  2021-12-06       Impact factor: 3.411

3.  Serum creatinine to cystatin C ratio reflects preoperative and early postoperative walking ability in older patients with hip fracture.

Authors:  Naoki Okubo; Takashi Yoshida; Kazuya Tanaka; Naoya Okada; Kunihiko Hosoi; Masato Ohara; Kenji Takahashi
Journal:  J Cachexia Sarcopenia Muscle       Date:  2022-02-15       Impact factor: 12.910

4.  Relationship Between Preoperative Hypoalbuminemia and Postoperative Pneumonia Following Geriatric Hip Fracture Surgery: A Propensity-Score Matched and Conditional Logistic Regression Analysis.

Authors:  Yunxu Tian; Yanbin Zhu; Kexin Zhang; Miao Tian; Shuhui Qin; Xiuting Li
Journal:  Clin Interv Aging       Date:  2022-04-13       Impact factor: 3.829

5.  A multicenter study of 1-year mortality and walking capacity after spinal fusion surgery for cervical fracture in elderly patients.

Authors:  Takeshi Sasagawa; Noriaki Yokogawa; Hiroyuki Hayashi; Hiroyuki Tsuchiya; Kei Ando; Hiroaki Nakashima; Naoki Segi; Kota Watanabe; Satoshi Nori; Kazuki Takeda; Takeo Furuya; Atsushi Yunde; Shota Ikegami; Masashi Uehara; Hidenori Suzuki; Yasuaki Imajo; Toru Funayama; Fumihiko Eto; Akihiro Yamaji; Ko Hashimoto; Yoshito Onoda; Kenichiro Kakutani; Yuji Kakiuchi; Nobuyuki Suzuki; Kenji Kato; Yoshinori Terashima; Ryosuke Hirota; Tomohiro Yamada; Tomohiko Hasegawa; Kenichi Kawaguchi; Yohei Haruta; Shoji Seki; Hitoshi Tonomura; Munehiro Sakata; Hiroshi Uei; Hirokatsu Sawada; Hiroyuki Tominaga; Hiroto Tokumoto; Takashi Kaito; Yoichi Iizuka; Eiji Takasawa; Yasushi Oshima; Hidetomi Terai; Koji Tamai; Bungo Otsuki; Masashi Miyazaki; Hideaki Nakajima; Kazuo Nakanishi; Kosuke Misaki; Gen Inoue; Katsuhito Kiyasu; Koji Akeda; Norihiko Takegami; Toshitaka Yoshii; Masayuki Ishihara; Seiji Okada; Yasuchika Aoki; Katsumi Harimaya; Hideki Murakami; Ken Ishii; Seiji Ohtori; Shiro Imagama; Satoshi Kato
Journal:  BMC Musculoskelet Disord       Date:  2022-08-20       Impact factor: 2.562

  5 in total

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