| Literature DB >> 32745682 |
Anneke Alkemade1, Martijn J Mulder2, Josephine M Groot3, Bethany R Isaacs4, Nikita van Berendonk3, Nicky Lute5, Scott Js Isherwood3, Pierre-Louis Bazin6, Birte U Forstmann3.
Abstract
Normative databases allow testing of novel hypotheses without the costly collection of magnetic resonance imaging (MRI) data. Here we present the Amsterdam Ultra-high field adult lifespan database (AHEAD). The AHEAD consists of 105 7 Tesla (T) whole-brain structural MRI scans tailored specifically to imaging of the human subcortex, including both male and female participants and covering the entire adult life span (18-80 yrs). We used these data to create probability maps for the subthalamic nucleus, substantia nigra, internal and external segment of the globus pallidus, and the red nucleus. Data was acquired at a submillimeter resolution using a multi-echo (ME) extension of the second gradient-echo image of the MP2RAGE sequence (MP2RAGEME) sequence, resulting in complete anatomical alignment of quantitative, R1-maps, R2*-maps, T1-maps, T1-weighted images, T2*-maps, and quantitative susceptibility mapping (QSM). Quantitative MRI maps, and derived probability maps of basal ganglia structures are freely available for further analyses.Entities:
Keywords: Basal ganglia; Probabilistic maps; Subcortex; Ultra-high field 7 Tesla structural MRI
Mesh：
Year: 2020 PMID： 32745682 DOI： 10.1016/j.neuroimage.2020.117200
Source DB: PubMed Journal: Neuroimage ISSN： 1053-8119 Impact factor: 6.556