Literature DB >> 32744553

A DNAzyme cascade for amplified detection of intracellular miRNA.

Yanan Wu1, Jing Li, Ke Quan, Xiangxian Meng, Xiaohai Yang, Jin Huang, Kemin Wang.   

Abstract

Inspired by the natural enzyme cascade reaction, an artificial DNAzyme cascade system is developed for the amplified detection of intracellular miR-141. The results showed that the method enormously enhanced the readout of the fluorescence signal and achieved a femtomolar detection limit.

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Year:  2020        PMID: 32744553     DOI: 10.1039/d0cc02847a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  Programming a DNA tetrahedral nanomachine as an integrative tool for intracellular microRNA biosensing and stimulus-unlocked target regulation.

Authors:  Lianyu Yu; Sha Yang; Zeyu Liu; Xiaopei Qiu; Xiaoqi Tang; Shuang Zhao; Hanqing Xu; Mingxuan Gao; Jing Bao; Ligai Zhang; Dan Luo; Kai Chang; Ming Chen
Journal:  Mater Today Bio       Date:  2022-05-06
  1 in total

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