Literature DB >> 32742009

Anti-infective Waste in a Pediatric Institution: Pinpointing Problems in the Process.

Christine E MacBrayne1, Manon C Williams1,2, Haley Obermeier1,2, Jason Child1, Justin W Heizer1, Matt Millard1, Kelly Pearce1, Casey Dugan1, Sarah K Parker1,2.   

Abstract

Purpose: At Children's Hospital Colorado (CHCO), there are approximately 40 000 inpatient anti-infective orders every year resulting over 100 000 dispenses. Significant quantities of anti-infectives are wasted, incurring roughly $100 000 in waste annually. Identifying areas for improvement will result in cost savings and ameliorate the impact of drug shortages. Summary: This descriptive report discusses the reasons for anti-infective waste at a free-standing, quaternary-care, pediatric hospital. The anti-infectives with the highest cost in waste ($) included meropenem ($38 084), micafungin ($21 690), amphotericin B liposome ($15 913). An internal audit of CHCO anti-infective waste revealed that drugs are wasted for the following reasons: patient discharge, medication order discontinuation or change, and misplaced doses.
Conclusion: The CHCO Antimicrobial Stewardship Program and the Pharmacy have proposed 4 process improvement measures that will target anti-infective waste to reduce pharmaceutical waste and hospital costs. These measures may be applicable to other drug classes that likely suffer from a similar proportion of waste.
© The Author(s) 2019.

Entities:  

Keywords:  anti-infective agents; anti-infective waste; antimicrobial stewardship; cost and cost analysis; pharmaceutical waste

Year:  2019        PMID: 32742009      PMCID: PMC7370351          DOI: 10.1177/0018578719844164

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  5 in total

1.  Intervention and Acceptance Rates Support Handshake-Stewardship Strategy.

Authors:  Amanda L Hurst; Jason Child; Sarah K Parker
Journal:  J Pediatric Infect Dis Soc       Date:  2019-05-11       Impact factor: 3.164

2.  Effect of provider-selected order indications on appropriateness of antimicrobial orders in a pediatric hospital.

Authors:  Yosuke Nomura; Madeleine Garcia; Jason Child; Amanda L Hurst; Daniel Hyman; Amy Poppy; Claire Palmer; Daksha Ranade; Laura Pyle; Sarah K Parker
Journal:  Am J Health Syst Pharm       Date:  2018-02-15       Impact factor: 2.637

3.  Core Elements of Outpatient Antibiotic Stewardship.

Authors:  Guillermo V Sanchez; Katherine E Fleming-Dutra; Rebecca M Roberts; Lauri A Hicks
Journal:  MMWR Recomm Rep       Date:  2016-11-11

4.  Handshake Stewardship: A Highly Effective Rounding-based Antimicrobial Optimization Service.

Authors:  Amanda L Hurst; Jason Child; Kelly Pearce; Claire Palmer; James K Todd; Sarah K Parker
Journal:  Pediatr Infect Dis J       Date:  2016-10       Impact factor: 2.129

5.  Anti-infective Acquisition Costs for a Stewardship Program: Getting to the Bottom Line.

Authors:  Sarah K Parker; Amanda L Hurst; Cary Thurm; Matthew Millard; Timothy C Jenkins; Jason Child; Casey Dugan
Journal:  Clin Infect Dis       Date:  2017-10-30       Impact factor: 9.079

  5 in total

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