Literature DB >> 32738845

Prevalence of Abnormal Liver Function Tests in COVID-19 Patients at a Tertiary Care Centre.

Atul Kaushik1, Showkat Nazir Wani2, Muneer Ahmad Baba2, A K Agarwal3.   

Abstract

BACKGROUND AND AIM: Coronavirus disease 2019 (COVID 2019) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is observed to cause liver dysfunction. We aimed to observe abnormal liver function tests (LFTs) in COVID-19 patients admitted in our hospital.
METHODS: It was a cross- sectional study involving 105 COVID-19 patients who were admitted in our Hospital from 03-04-2020 to 02-05-2020. The COVID-19 positivity was defined on basis of real-time PCR. Thorough clinical examination and laboratory investigations including Complete Blood Count, Renal function Tests, Liver Function Tests, Chest X-ray, ECG, etc. were done.
RESULTS: The total number of male and female patients were 64 and 41. Out of total 105 patients, 62 i.e. 59.04% had abnormal LFTs at time of admission. Out of these 62 patients, 44(70.9%) were Male and 18(29.03%) were female. Only 5(4.76%) patients had abnormal LFTs on repeat testing. Median Age of patients was 33years. Average stay of patients with Abnormal LFTs was 15 days (10-16 days) as compared to 10 days (7-11days) for patients with normal LFTs.
CONCLUSION: The prevalence of Abnormal Liver function tests in patients of COVID-19 is 59.04%. Abnormal liver functions were more in males. The average stay in hospital for COVID-19 patients with abnormal LFTs was longer than those with normal LFTs. © Journal of the Association of Physicians of India 2011.

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Year:  2020        PMID: 32738845

Source DB:  PubMed          Journal:  J Assoc Physicians India        ISSN: 0004-5772


  5 in total

1.  Covid-19 and Gastrointestinal Manifestations in Indian Patients: A Meta-Analysis.

Authors:  Lakshmi Gayathri Chirumamilla; Hassan Brim; Antonio Pizuorno; Gholamreza Oskrochi; Hassan Ashktorab
Journal:  SOJ Microbiol Infect Dis       Date:  2021-09-10

Review 2.  COVID-19 and liver dysfunction: What nutritionists need to know.

Authors:  Ming-Ke Wang; Xue-Lu Yu; Li-Yun Zhou; Hong-Mei Si; Ju-Fen Hui; Deng-Yong Hou; Wei-Peng Li; Ji-Shun Yang
Journal:  World J Gastroenterol       Date:  2022-04-21       Impact factor: 5.374

3.  Liver function tests in COVID 19: A retrospective record-based study from a tertiary care centre in urban Maharashtra, India.

Authors:  Dharmendra Kumar; Sharad Srivastava; T Rajnikant; Saurabh Dawra; M S Tevatia; Reema Mukherjee
Journal:  Med J Armed Forces India       Date:  2022-05-13

4.  Clinical Significance of Liver Function Abnormality in Patients with COVID-19: A Single-center Experience from Western India.

Authors:  Chetan R Kalal; Harshad Joshi; Vivek Kumar; Divya Gopal; Darshana Rathod; Ashish Shukla; Tarang Gianchandani; Chetan Bhatt
Journal:  J Clin Transl Hepatol       Date:  2021-05-13

Review 5.  Abnormal Liver Biochemistry Tests and Acute Liver Injury in COVID-19 Patients: Current Evidence and Potential Pathogenesis.

Authors:  Donovan A McGrowder; Fabian Miller; Melisa Anderson Cross; Lennox Anderson-Jackson; Sophia Bryan; Lowell Dilworth
Journal:  Diseases       Date:  2021-07-01
  5 in total

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