Fatimah Al Hassan1, Marwah Aljahli2, Fadel Molani3, Ali Almomen2. 1. Department of Surgery, King Fahad Specialist Hospital, Al Muraikebat Area, Ammar Bin Thabet Street, PO Box 15215, Dammam, 31444, Saudi Arabia. Electronic address: alhassanfatimah@gmail.com. 2. Department of Surgery, King Fahad Specialist Hospital, Al Muraikebat Area, Ammar Bin Thabet Street, PO Box 15215, Dammam, 31444, Saudi Arabia. 3. Department of Medical Imaging, King Fahad Specialist Hospital, Al Muraikebat Area, Ammar Bin Thabet Street, PO Box 15215, Dammam, 31444, Saudi Arabia.
Abstract
INTRODUCTION: Mucormycosis is a rare, aggressive, and invasive disease with a fatal outcome. It most commonly affects patients with compromised immunity, particularly those with poorly controlled diabetes. We present a case series of patients with uncontrolled diabetes and mucormycosis. PRESENTATION OF CASE: We present a series of three patients with uncontrolled diabetes, with main symptoms of paranasal sinusitis, nasal discharge, ophthalmic changes, and facial nerve involvement. Diagnoses of mucormycosis were made via microbiological testing and computed tomography. These cases were managed by combination therapy of tight glycemic control, urgent endoscopic sinus debridement, and antifungal therapy. DISCUSSION: Diagnosing rhino-orbito-cerebral mucormycosis requires a high degree of suspicion and both microbiologic and microscopic evidence. Better clinical outcomes can be obtained by combining medical and surgical management. CONCLUSION: We describe our experience in handling three cases of poorly controlled diabetes with rhino-orbito-cerebral mucormycosis.
INTRODUCTION: Mucormycosis is a rare, aggressive, and invasive disease with a fatal outcome. It most commonly affects patients with compromised immunity, particularly those with poorly controlled diabetes. We present a case series of patients with uncontrolled diabetes and mucormycosis. PRESENTATION OF CASE: We present a series of three patients with uncontrolled diabetes, with main symptoms of paranasal sinusitis, nasal discharge, ophthalmic changes, and facial nerve involvement. Diagnoses of mucormycosis were made via microbiological testing and computed tomography. These cases were managed by combination therapy of tight glycemic control, urgent endoscopic sinus debridement, and antifungal therapy. DISCUSSION: Diagnosing rhino-orbito-cerebral mucormycosis requires a high degree of suspicion and both microbiologic and microscopic evidence. Better clinical outcomes can be obtained by combining medical and surgical management. CONCLUSION: We describe our experience in handling three cases of poorly controlled diabetes with rhino-orbito-cerebral mucormycosis.