Ewa Rojczyk1, Agnieszka Klama-Baryła2, Wojciech Łabuś3, Katarzyna Wilemska-Kucharzewska4, Marek Kucharzewski5. 1. Department of Descriptive and Topographic Anatomy, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 19 Jordana Street, 41-808, Zabrze, Poland. Electronic address: ewarojczyk@gmail.com. 2. The Burn Centre of Stanisław Sakiel, 2 Jana Pawła II Street, 41-100, Siemianowice Śląskie, Poland. Electronic address: agawa777.78@gmail.com. 3. The Burn Centre of Stanisław Sakiel, 2 Jana Pawła II Street, 41-100, Siemianowice Śląskie, Poland. Electronic address: wojciech.labus@gmail.com. 4. Department of Internal Medicine, School of Public Health in Bytom, Medical University of Silesia, 7 Żeromskiego Street, 41-902, Bytom, Poland. Electronic address: kkucharzewska@sum.edu.pl. 5. Department of Descriptive and Topographic Anatomy, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, 19 Jordana Street, 41-808, Zabrze, Poland; The Burn Centre of Stanisław Sakiel, 2 Jana Pawła II Street, 41-100, Siemianowice Śląskie, Poland. Electronic address: kucharzewskimarek@poczta.onet.pl.
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: The history of medical application of propolis (also known as bee glue) dates back to the times of ancient Greeks, Romans, Persians and Egyptians. Honey and other bee products, including propolis, occupy an important place in Polish folk medicine. Scientific research on propolis in Poland began in the early 1960s in Zabrze and continues until now. AIM OF THE REVIEW: The aim of this review is to provide an overview of information on Polish research on propolis and its medical application with particular emphasis on studies concerning wound healing. Consequently, our goal is also to shed a new light on therapeutic potential of Polish propolis in order to support future research in the field. MATERIALS AND METHODS: A systematic review of scientific literature on propolis and its medical application was performed by using the literature databases (PubMed, Web of Science, Google Scholar). We paid special attention to papers describing the effect of propolis on skin wound healing as well as to Polish contribution to research on propolis. RESULTS: Professor Stan Scheller was the first Polish scientist dealing with propolis and its medical potential. His legacy was continued by several research teams that studied the topic in various aspects. They analyzed propolis composition, its antioxidant, anti-inflammatory, antimicrobial, antiapoptotic and anticancer properties as well as its application in dentistry and wound treatment. Burn wound healing physiology after propolis administration was thoroughly studied on pig model, whereas research on patients proved the efficacy of propolis in chronic venous leg ulcer treatment. CONCLUSION: Polish scientists have made a significant contribution to the research on propolis, its biological properties and influence on wound healing. Propolis ointments can effectively accelerate the healing process and improve healing physiology, so they can be recommended as a promising topical medication for wound treatment in the future clinical and preclinical trials.
ETHNOPHARMACOLOGICAL RELEVANCE: The history of medical application of propolis (also known as bee glue) dates back to the times of ancient Greeks, Romans, Persians and Egyptians. Honey and other bee products, including propolis, occupy an important place in Polish folk medicine. Scientific research on propolis in Poland began in the early 1960s in Zabrze and continues until now. AIM OF THE REVIEW: The aim of this review is to provide an overview of information on Polish research on propolis and its medical application with particular emphasis on studies concerning wound healing. Consequently, our goal is also to shed a new light on therapeutic potential of Polish propolis in order to support future research in the field. MATERIALS AND METHODS: A systematic review of scientific literature on propolis and its medical application was performed by using the literature databases (PubMed, Web of Science, Google Scholar). We paid special attention to papers describing the effect of propolis on skin wound healing as well as to Polish contribution to research on propolis. RESULTS: Professor Stan Scheller was the first Polish scientist dealing with propolis and its medical potential. His legacy was continued by several research teams that studied the topic in various aspects. They analyzed propolis composition, its antioxidant, anti-inflammatory, antimicrobial, antiapoptotic and anticancer properties as well as its application in dentistry and wound treatment. Burn wound healing physiology after propolis administration was thoroughly studied on pig model, whereas research on patients proved the efficacy of propolis in chronic venous leg ulcer treatment. CONCLUSION: Polish scientists have made a significant contribution to the research on propolis, its biological properties and influence on wound healing. Propolis ointments can effectively accelerate the healing process and improve healing physiology, so they can be recommended as a promising topical medication for wound treatment in the future clinical and preclinical trials.
Authors: Dolly Patricia Pardo-Mora; Oscar Julián Murillo; Mauricio Rey-Buitrago; Mónica Losada-Barragán; Jaime Fabian Cruz Uribe; Karina Basso Santiago; Bruno José Conti; Eliza de Oliveira Cardoso; Fernanda Lopes Conte; Rafael María Gutiérrez; Orlando Torres García; José Maurício Sforcin Journal: Vet World Date: 2021-04-22
Authors: Agnes Chacor de Figueiredo; Javier Mauricio Anaya-Mancipe; Aline Oliveira da Silva de Barros; Ralph Santos-Oliveira; Marcos Lopes Dias; Rossana Mara da Silva Moreira Thiré Journal: Molecules Date: 2022-08-22 Impact factor: 4.927