Literature DB >> 32733980

Prevalence of Comorbidities in COVID-19 Patients: A Systematic Review and Meta-Analysis.

Ashkan Baradaran1, Mohammad H Ebrahimzadeh1, Aslan Baradaran2, Amir R Kachooei1.   

Abstract

BACKGROUND: In this study, we aimed to assess the prevalence of comorbidities in the confirmed COVID-19 patients. This might help showing which comorbidity might pose the patients at risk of more severe symptoms.
METHODS: We searched all relevant databases on April 7th, 2020 using the keywords ("novel coronavirus" OR COVID-19 OR SARS-CoV-2 OR Coronavirus) AND (comorbidities OR clinical characteristics OR epidemiologic*). We reviewed 33 papers' full text out of 1053 papers. There were 32 papers from China and 1 from Taiwan. There was no language or study level limit. Prevalence of comorbidities including hypertension, diabetes mellitus, cardiovascular disease, chronic lung disease, chronic kidney disease, malignancies, cerebrovascular diseases, chronic liver disease and smoking were extracted to measure the pooled estimates. We used OpenMeta and used random-effect model to do a single arm meta-analysis.
RESULTS: The mean age of the diagnosed patients was 51 years. The male to female ratio was 55 to 45. The most prevalent finding in the confirmed COVID-19 patients was hypertension, which was found in 1/5 of the patients (21%). Other most prevalent finding was diabetes mellitus (DM) in 11%, cerebrovascular disease in 2.4%, cardiovascular disease in 5.8%, chronic kidney disease in 3.6%, chronic liver disease in 2.9%, chronic pulmonary disease in 2.0%, malignancy in 2.7%, and smoking in 8.7% of the patients.
CONCLUSION: COVID-19 infection seems to be affecting every race, sex, age, irrespective of health status. The risk of symptomatic and severe disease might be higher due to the higher age which is usually accompanied with comorbidities. However, comorbidities do not seem to be the prerequisite for symptomatic and severe COVID-19 infection, except hypertension.

Entities:  

Keywords:  COVID-19; Comorbidities; Coronavirus; Systematic review

Year:  2020        PMID: 32733980      PMCID: PMC7296605          DOI: 10.22038/abjs.2020.47754.2346

Source DB:  PubMed          Journal:  Arch Bone Jt Surg        ISSN: 2345-461X


  31 in total

1.  Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.

Authors:  Dawei Wang; Bo Hu; Chang Hu; Fangfang Zhu; Xing Liu; Jing Zhang; Binbin Wang; Hui Xiang; Zhenshun Cheng; Yong Xiong; Yan Zhao; Yirong Li; Xinghuan Wang; Zhiyong Peng
Journal:  JAMA       Date:  2020-03-17       Impact factor: 56.272

2.  COVID-19 in a designated infectious diseases hospital outside Hubei Province, China.

Authors:  Qingxian Cai; Deliang Huang; Pengcheng Ou; Hong Yu; Zhibin Zhu; Zhang Xia; Yinan Su; Zhenghua Ma; Yiming Zhang; Zhiwei Li; Qing He; Lei Liu; Yang Fu; Jun Chen
Journal:  Allergy       Date:  2020-04-17       Impact factor: 13.146

3.  Clinical Features and Short-term Outcomes of 102 Patients with Coronavirus Disease 2019 in Wuhan, China.

Authors:  Jianlei Cao; Wen-Jun Tu; Wenlin Cheng; Lei Yu; Ya-Kun Liu; Xiaorong Hu; Qiang Liu
Journal:  Clin Infect Dis       Date:  2020-07-28       Impact factor: 9.079

4.  Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.

Authors:  Chaolin Huang; Yeming Wang; Xingwang Li; Lili Ren; Jianping Zhao; Yi Hu; Li Zhang; Guohui Fan; Jiuyang Xu; Xiaoying Gu; Zhenshun Cheng; Ting Yu; Jiaan Xia; Yuan Wei; Wenjuan Wu; Xuelei Xie; Wen Yin; Hui Li; Min Liu; Yan Xiao; Hong Gao; Li Guo; Jungang Xie; Guangfa Wang; Rongmeng Jiang; Zhancheng Gao; Qi Jin; Jianwei Wang; Bin Cao
Journal:  Lancet       Date:  2020-01-24       Impact factor: 79.321

5.  Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series.

Authors:  Xiao-Wei Xu; Xiao-Xin Wu; Xian-Gao Jiang; Kai-Jin Xu; Ling-Jun Ying; Chun-Lian Ma; Shi-Bo Li; Hua-Ying Wang; Sheng Zhang; Hai-Nv Gao; Ji-Fang Sheng; Hong-Liu Cai; Yun-Qing Qiu; Lan-Juan Li
Journal:  BMJ       Date:  2020-02-19

6.  Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China.

Authors:  L Zhang; F Zhu; L Xie; C Wang; J Wang; R Chen; P Jia; H Q Guan; L Peng; Y Chen; P Peng; P Zhang; Q Chu; Q Shen; Y Wang; S Y Xu; J P Zhao; M Zhou
Journal:  Ann Oncol       Date:  2020-03-26       Impact factor: 32.976

7.  Kidney disease is associated with in-hospital death of patients with COVID-19.

Authors:  Yichun Cheng; Ran Luo; Kun Wang; Meng Zhang; Zhixiang Wang; Lei Dong; Junhua Li; Ying Yao; Shuwang Ge; Gang Xu
Journal:  Kidney Int       Date:  2020-03-20       Impact factor: 10.612

8.  Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan.

Authors:  Wen-Hsin Hsih; Meng-Yu Cheng; Mao-Wang Ho; Chia-Huei Chou; Po-Chang Lin; Chih-Yu Chi; Wei-Chih Liao; Chih-Yu Chen; Lih-Ying Leong; Ni Tien; Huan-Cheng Lai; Yi-Chyi Lai; Min-Chi Lu
Journal:  J Microbiol Immunol Infect       Date:  2020-03-13       Impact factor: 4.399

9.  Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms.

Authors:  Xi Jin; Jiang-Shan Lian; Jian-Hua Hu; Jianguo Gao; Lin Zheng; Yi-Min Zhang; Shao-Rui Hao; Hong-Yu Jia; Huan Cai; Xiao-Li Zhang; Guo-Dong Yu; Kai-Jin Xu; Xiao-Yan Wang; Jue-Qing Gu; Shan-Yan Zhang; Chan-Yuan Ye; Ci-Liang Jin; Ying-Feng Lu; Xia Yu; Xiao-Peng Yu; Jian-Rong Huang; Kang-Li Xu; Qin Ni; Cheng-Bo Yu; Biao Zhu; Yong-Tao Li; Jun Liu; Hong Zhao; Xuan Zhang; Liang Yu; Yong-Zheng Guo; Jun-Wei Su; Jing-Jing Tao; Guan-Jing Lang; Xiao-Xin Wu; Wen-Rui Wu; Ting-Ting Qv; Dai-Rong Xiang; Ping Yi; Ding Shi; Yanfei Chen; Yue Ren; Yun-Qing Qiu; Lan-Juan Li; Jifang Sheng; Yida Yang
Journal:  Gut       Date:  2020-03-24       Impact factor: 23.059

10.  Analysis of Epidemiological and Clinical Features in Older Patients With Coronavirus Disease 2019 (COVID-19) Outside Wuhan.

Authors:  Jiangshan Lian; Xi Jin; Shaorui Hao; Huan Cai; Shanyan Zhang; Lin Zheng; Hongyu Jia; Jianhua Hu; Jianguo Gao; Yimin Zhang; Xiaoli Zhang; Guodong Yu; Xiaoyan Wang; Jueqing Gu; Chanyuan Ye; Ciliang Jin; Yingfeng Lu; Xia Yu; Xiaopeng Yu; Yue Ren; Yunqing Qiu; Lanjuan Li; Jifang Sheng; Yida Yang
Journal:  Clin Infect Dis       Date:  2020-07-28       Impact factor: 9.079

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  26 in total

1.  Complications and Comorbidities in COVID-19 Patients: A Comparative study.

Authors:  Omair H Al-Hussain
Journal:  Cureus       Date:  2022-08-31

2.  Clinical outcomes of coronavirus disease 2019 in liver transplant recipients.

Authors:  Muhammad Shafiq; Cheryl Gibson
Journal:  World J Hepatol       Date:  2022-06-27

3.  Sociodemographic determinants and clinical risk factors associated with COVID-19 severity: a cross-sectional analysis of over 200,000 patients in Tehran, Iran.

Authors:  Mohammad-Reza Sohrabi; Rozhin Amin; Ali Maher; Ayad Bahadorimonfared; Shahriar Janbazi; Khatereh Hannani; Ali-Asghar Kolahi; Ali-Reza Zali
Journal:  BMC Infect Dis       Date:  2021-05-25       Impact factor: 3.090

4.  Assessment of Knowledge, Attitude, and Practice of Security and Safety Workers Toward the COVID-19 Pandemic: A Cross-Sectional Study.

Authors:  Maha M AlRasheed; Abdullah M Alsugair; Hala F Almarzouqi; Gadah K Alonazi; Fadilah S Aleanizy; Fulwah Y Alqahtani; Gamal A Shazly; Fowad Khurshid
Journal:  Front Public Health       Date:  2021-04-28

Review 5.  A meta-meta-analysis: Evaluation of meta-analyses published in the effectiveness of cardiovascular comorbidities on the severity of COVID-19.

Authors:  Mehri Bemani Naeini; Mahdieh Sahebi; Fateme Nikbakht; Zahra Jamshidi; Mahnaz Ahmadimanesh; Maryam Hashemi; Javad Ramezani; Hamid Heidarian Miri; Rezvan Yazdian-Robati
Journal:  Obes Med       Date:  2021-01-23

6.  The characteristics of cancerous patients infected with COVID-19 in hospital setting.

Authors:  Amir Sadeghi; Arash Dooghaie Moghadam; Pegah Eslami; Ali Pirsalehi; Sajad Shojaee; Ghazal Sanadgol; Laya Jalilian Khave; Mohammad Vahidi; Hamid Asadzadeh Aghdaei; Ehsan Nazemalhosseini Mojarad
Journal:  Acta Biomed       Date:  2020-11-10

7.  Clinical characteristics of asymptomatic and symptomatic COVID-19 patients in the Eastern Province of Saudi Arabia.

Authors:  Jumana Mansour AlJishi; Alya Hassan Alhajjaj; Fatimah Lateef Alkhabbaz; Taaweel Hussain AlAbduljabar; Ahmad Alsaif; Hussain Alsaif; Kawther Saeed Alomran; Ghada Ali Aljanobi; Zainab Alghawi; Mohammed Alsaif; Jaffar A Al-Tawfiq
Journal:  J Infect Public Health       Date:  2020-12-17       Impact factor: 3.718

Review 8.  COVID-19: Case fatality and ACE2 inhibitors treatment concerns in patients with comorbidities.

Authors:  Rokhsareh Aghili; Maryam Honardoost; Mohammad E Khamseh
Journal:  Med J Islam Repub Iran       Date:  2020-11-02

9.  Comorbidities and clinical features related to severe outcomes among COVID-19 cases in Selangor, Malaysia.

Authors:  Wan Shakira Rodzlan Hasani; Shubash Shander Ganapathy; Chong Zhuo Lin; Halizah Mat Rifin; Mohammad Nazarudin Bahari; Muhammad Haikal Ghazali; Noor Aliza Lodz; Muhd Hafizuddin Taufik Ramli; Nur Liana Ab Majid; Miaw Yn Jane Ling; Muhammad Fadhli Mohd Yusoff; Noor Ani Ahmad; Anita Suleiman; Ahmad Faudzi Yusoff; Venugopalan Balan; Sha'ari Ngadiman
Journal:  Western Pac Surveill Response J       Date:  2021-02-16

10.  A Systematic Review and Meta-Analysis of Hospitalised Current Smokers and COVID-19.

Authors:  Jesus González-Rubio; Carmen Navarro-López; Elena López-Nájera; Ana López-Nájera; Lydia Jiménez-Díaz; Juan D Navarro-López; Alberto Nájera
Journal:  Int J Environ Res Public Health       Date:  2020-10-11       Impact factor: 3.390

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