| Literature DB >> 32733595 |
Abstract
To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin's Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy.Entities:
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Year: 2020 PMID: 32733595 PMCID: PMC7369659 DOI: 10.1155/2020/6584323
Source DB: PubMed Journal: Comput Math Methods Med ISSN: 1748-670X Impact factor: 2.238