| Literature DB >> 32733078 |
Masahiko Isaka1, Malipan Sappan2, Wilunda Choowong2, Thitiya Boonpratuang3, Rattaket Choeyklin3, Tao Feng4, Ji-Kai Liu4.
Abstract
Ten previously undescribed lanostane-type triterpenoids (1-10), together with 15 known lanostanes, were isolated from artificially cultivated fruiting bodies of the basidiomycete Ganoderma sp. BCC 21329. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data and by application of the modified Mosher's method. Compounds 1, 3, 5, and 7 showed moderate antimalarial activity (IC50 3.8-7.6 μg ml-1).Entities:
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Year: 2020 PMID： 32733078 DOI： 10.1038/s41429-020-0357-7
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649