| Literature DB >> 32729433 |
Abdul Mannan Baig1, Saara Ahmad1, Areeba Khaleeq1, Hamna Rafique1, Shafiqa Rajput1, Meher Angez1, Ayesha Nasir Hameed1, Talha Nawaz1, Preet Katyara1.
Abstract
Ocular tissues can serve as a reservoir for the SARS-CoV-2 virus which can not only cause conjunctivitis but also serve as a resource of infection transmission to others. Additionally, the eye and its tear drainage apparatus can track the SARS-CoV-2 from the eye into the respiratory tract of the patient. The potential ocular presence of the SARS-CoV-2 in the eye of a patient can target ACE2 receptors in the endothelium of the conjunctival vessels and use the lacrimal sac a potential space to evade immune detection and clinical isolation. The recently reported case of COVID-19 after the acquisition of SARS-CoV-2 from a COVID-19 patient should alert the healthcare professionals dealing with COIVD-19 patients as wear-ing masks alone cannot guarantee protection against infection transmission. Further studies, like isolation of SARS-CoV-2 from the eyes of patients with COVID-19, needed to identify the eyes as a potential source of SARS-CoV-2 infection trans-mission. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: ACE2 receptors; COVID-19; Ocular viral infections.; SARS-CoV-2
Year: 2020 PMID: 32729433 DOI: 10.2174/1871526520999200729182242
Source DB: PubMed Journal: Infect Disord Drug Targets ISSN: 1871-5265