Literature DB >> 32729433

Ocular COVID-19: Eyes as a reservoir to conceal and spread SARS-CoV-2.

Abdul Mannan Baig1, Saara Ahmad1, Areeba Khaleeq1, Hamna Rafique1, Shafiqa Rajput1, Meher Angez1, Ayesha Nasir Hameed1, Talha Nawaz1, Preet Katyara1.   

Abstract

Ocular tissues can serve as a reservoir for the SARS-CoV-2 virus which can not only cause conjunctivitis but also serve as a resource of infection transmission to others. Additionally, the eye and its tear drainage apparatus can track the SARS-CoV-2 from the eye into the respiratory tract of the patient. The potential ocular presence of the SARS-CoV-2 in the eye of a patient can target ACE2 receptors in the endothelium of the conjunctival vessels and use the lacrimal sac a potential space to evade immune detection and clinical isolation. The recently reported case of COVID-19 after the acquisition of SARS-CoV-2 from a COVID-19 patient should alert the healthcare professionals dealing with COIVD-19 patients as wear-ing masks alone cannot guarantee protection against infection transmission. Further studies, like isolation of SARS-CoV-2 from the eyes of patients with COVID-19, needed to identify the eyes as a potential source of SARS-CoV-2 infection trans-mission. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  ACE2 receptors; COVID-19; Ocular viral infections.; SARS-CoV-2

Year:  2020        PMID: 32729433     DOI: 10.2174/1871526520999200729182242

Source DB:  PubMed          Journal:  Infect Disord Drug Targets        ISSN: 1871-5265


  3 in total

1.  Mucosal Antibody Response to SARS-CoV-2 in Paediatric and Adult Patients: A Longitudinal Study.

Authors:  Renee W Y Chan; Kate C C Chan; Grace C Y Lui; Joseph G S Tsun; Kathy Y Y Chan; Jasmine S K Yip; Shaojun Liu; Michelle W L Yu; Rita W Y Ng; Kelvin K L Chong; Maggie H Wang; Paul K S Chan; Albert M Li; Hugh Simon Lam
Journal:  Pathogens       Date:  2022-03-24

2.  Chronic long-COVID syndrome: A protracted COVID-19 illness with neurological dysfunctions.

Authors:  Abdul Mannan Baig
Journal:  CNS Neurosci Ther       Date:  2021-10-09       Impact factor: 5.243

3.  International survey of ophthalmic anaesthesia service provision, protection of anaesthesia providers and patients during COVID-19 pandemic: a wake-up call.

Authors:  Shashi B Vohra; Chandra M Kumar
Journal:  Eye (Lond)       Date:  2022-02-26       Impact factor: 4.456

  3 in total

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