Literature DB >> 32725424

Neuro-regenerative potential of dental stem cells: a concise review.

Duaa Abuarqoub1,2, Nazneen Aslam3, Bayan Almajali4, Leen Shajrawi4, Hanan Jafar3,4, Abdalla Awidi5,6.   

Abstract

This review will summarize the research information regarding the regenerative potential of dental stem cells for the treatment of neurodegenerative disorders. As compared to existing treatment modalities, the stem cell therapy seems promising, and accumulating evidences about the differentiation of stem cells into various lineages are proving it. The incidence of neurodegenerative diseases such as Alzheimer's, Parkinson's, stroke, and peripheral neuropathy is increasing due to the rise in life expectancies of people which have put a huge burden on economies. Finding a promising treatment could benefit not only the patients but also the communities. Dental stem cells hold a great potential to differentiate into neuronal cells. Many studies have reported the differentiation potential of the dental stem cells with the presence of neuronal lineage markers. In this review, we conferred how the use of dental stem cells can benefit the above-mentioned bedridden diseases.

Entities:  

Keywords:  Dental; Differentiation; Neuro-degenerative disorders; Neuro-regeneration; Stem cells

Mesh:

Year:  2020        PMID: 32725424     DOI: 10.1007/s00441-020-03255-0

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN: 0302-766X            Impact factor:   5.249


  84 in total

Review 1.  Taking a bite out of spinal cord injury: do dental stem cells have the teeth for it?

Authors:  John Bianco; Pauline De Berdt; Ronald Deumens; Anne des Rieux
Journal:  Cell Mol Life Sci       Date:  2016-01-14       Impact factor: 9.261

2.  In vivo integration of poly(ε-caprolactone)/gelatin nanofibrous nerve guide seeded with teeth derived stem cells for peripheral nerve regeneration.

Authors:  Mohammad-Hossein Beigi; Laleh Ghasemi-Mobarakeh; Molamma P Prabhakaran; Khadijeh Karbalaie; Hamid Azadeh; Seeram Ramakrishna; Hossein Baharvand; Mohammad-Hossein Nasr-Esfahani
Journal:  J Biomed Mater Res A       Date:  2014-03-03       Impact factor: 4.396

Review 3.  Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair.

Authors:  Bruno Battiston; Stefano Geuna; Matteo Ferrero; Pierluigi Tos
Journal:  Microsurgery       Date:  2005       Impact factor: 2.425

4.  Human Dental Pulp Stem Cells Differentiate into Oligodendrocyte Progenitors Using the Expression of Olig2 Transcription Factor.

Authors:  Nahid Askari; Mohammad Mehdi Yaghoobi; Mehdi Shamsara; Saeed Esmaeili-Mahani
Journal:  Cells Tissues Organs       Date:  2015-05-07       Impact factor: 2.481

Review 5.  Human mesenchymal stem cells: from basic biology to clinical applications.

Authors:  B M Abdallah; M Kassem
Journal:  Gene Ther       Date:  2007-11-08       Impact factor: 5.250

6.  Tetracycline-regulated expression of OLIG2 gene in human dental pulp stem cells lead to mouse sciatic nerve regeneration upon transplantation.

Authors:  N Askari; M M Yaghoobi; M Shamsara; S Esmaeili-Mahani
Journal:  Neuroscience       Date:  2015-08-05       Impact factor: 3.590

7.  Comparative characterization of STRO-1(neg)/CD146(pos) and STRO-1(pos)/CD146(pos) apical papilla stem cells enriched with flow cytometry.

Authors:  A Bakopoulou; G Leyhausen; J Volk; P Koidis; W Geurtsen
Journal:  Arch Oral Biol       Date:  2013-07-18       Impact factor: 2.633

8.  Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues.

Authors:  Agnes Arthur; Grigori Rychkov; Songtao Shi; Simon Andrea Koblar; Stan Gronthos
Journal:  Stem Cells       Date:  2008-05-22       Impact factor: 6.277

9.  The neuroprotective effect of dental pulp cells in models of Alzheimer's and Parkinson's disease.

Authors:  C Apel; O V Forlenza; V J R de Paula; L L Talib; B Denecke; C P Eduardo; W F Gattaz
Journal:  J Neural Transm (Vienna)       Date:  2008-10-30       Impact factor: 3.575

10.  Multimodal Approaches for Regenerative Stroke Therapies: Combination of Granulocyte Colony-Stimulating Factor with Bone Marrow Mesenchymal Stem Cells is Not Superior to G-CSF Alone.

Authors:  Adrian Tudor Balseanu; Ana-Maria Buga; Bogdan Catalin; Daniel-Christoph Wagner; Johannes Boltze; Ana-Maria Zagrean; Klaus Reymann; Wolf Schaebitz; Aurel Popa-Wagner
Journal:  Front Aging Neurosci       Date:  2014-06-23       Impact factor: 5.750

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