Literature DB >> 32725306

Renal pelvis urine Gram stain as a traditional, but new marker in predicting postoperative fever and stone culture positivity in percutaneous nephrolithotomy: an observational, prospective, non-randomized cohort study.

Nejdet Karsiyakali1, Ugur Yucetas2, Aysel Karatas3, Emre Karabay4, Emrah Okucu2, Erkan Erkan2.   

Abstract

PURPOSE: The aim of this study was to evaluate the diagnostic value of renal pelvis urine Gram staining (RPUGS) in predicting postoperative fever and renal stone culture (RSC) positivity in percutaneous nephrolithotomy (PCNL).
METHODS: Totally 141 consecutive patients undergoing PCNL for renal stone were included between January 2018 and December 2019. The RPUGS and renal pelvis urine culture (RPUC) were performed using urine sample from renal collecting system, while RSC was performed using stone fragments. Patients were divided into two groups as Group 1 (n = 119) without postoperative fever (< 38 °C) and Group 2 (n = 22) with postoperative fever (≥ 38 °C). Stone culture and Gram staining models were created for predicting postoperative fever using constant covariates of the presence of residual stone, hydronephrosis, and stone burden.
RESULTS: A significantly higher number of patients in Group 2 had RPUGS, RSC, and RPUC positivity (p < 0.001, for each). The sensitivity, specificity, positive predictive value, and negative predictive value of RPUGS in predicting postoperative fever were 72.7%, 89.9%, 57.1%, and 94.7%, respectively. It was observed that both models had similar predictive values and diagnostic performances. Although RSC and RPUGS had a similar diagnostic value in predicting postoperative fever in univariable analysis, both were found to be independent predictors in multivariable analysis (OR: 10.6, 95% CI 4.07-27.9, p < 0.001 and OR: 15.0, 95% CI 5.4-41.2, p < 0.001, respectively).
CONCLUSIONS: In conclusion, RPUGS is as effective as RSC in predicting fever after PCNL. We recommend RPUGS during PCNL to manage post-PCNL infectious complications.

Entities:  

Keywords:  Complications; Gram stain; Infections; Nephrolithiasis; Percutaneous nephrolithotomy; Stone culture

Year:  2020        PMID: 32725306     DOI: 10.1007/s00345-020-03381-y

Source DB:  PubMed          Journal:  World J Urol        ISSN: 0724-4983            Impact factor:   4.226


  27 in total

1.  Post-percutaneous nephrolithotomy systemic inflammatory response: a prospective analysis of preoperative urine, renal pelvic urine and stone cultures.

Authors:  Ruslan Korets; Joseph A Graversen; Max Kates; Adam C Mues; Mantu Gupta
Journal:  J Urol       Date:  2011-09-23       Impact factor: 7.450

2.  Clinical implication of routine stone culture in percutaneous nephrolithotomy--a prospective study.

Authors:  D Margel; Y Ehrlich; N Brown; D Lask; P M Livne; D A Lifshitz
Journal:  Urology       Date:  2006-01       Impact factor: 2.649

3.  Risk factors for postoperative infectious complications following percutaneous nephrolithotomy: a prospective clinical study.

Authors:  Omer Koras; Ibrahim Halil Bozkurt; Tarik Yonguc; Tansu Degirmenci; Burak Arslan; Bulent Gunlusoy; Ozgu Aydogdu; Suleyman Minareci
Journal:  Urolithiasis       Date:  2014-10-01       Impact factor: 3.436

Review 4.  Direct Gram staining and its various benefits in the diagnosis of bacterial infections.

Authors:  Lyudmila Boyanova
Journal:  Postgrad Med       Date:  2017-11-01       Impact factor: 3.840

5.  Predictive factors of infectious complications in the postoperative of percutaneous nephrolithotomy.

Authors:  L Lorenzo Soriano; D G Ordaz Jurado; J Pérez Ardavín; A Budía Alba; P Bahílo Mateu; M Trassierra Villa; D López Acón
Journal:  Actas Urol Esp (Engl Ed)       Date:  2018-11-08

6.  Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study.

Authors:  Annerleim Walton-Diaz; José Ignacio Vinay; Jaime Barahona; Pieter Daels; Mariano González; Juan Pablo Hidalgo; Cristian Palma; Pablo Díaz; Alfredo Domenech; Rodrigo Valenzuela; Fernando Marchant
Journal:  Int Urol Nephrol       Date:  2016-11-15       Impact factor: 2.370

7.  Percutaneous nephrolithotomy for infection stones: what is the risk for postoperative sepsis? A retrospective cohort study.

Authors:  Ohad Shoshany; David Margel; Camil Finz; Orly Ben-Yehuda; Pinhas M Livne; Ronen Holand; David Lifshitz
Journal:  Urolithiasis       Date:  2015-01-01       Impact factor: 3.436

8.  Stone and pelvic urine culture and sensitivity are better than bladder urine as predictors of urosepsis following percutaneous nephrolithotomy: a prospective clinical study.

Authors:  Paramananthan Mariappan; Gordon Smith; Simon V Bariol; Sami A Moussa; David A Tolley
Journal:  J Urol       Date:  2005-05       Impact factor: 7.450

9.  Preoperative Bladder Urine Culture as a Predictor of Intraoperative Stone Culture Results: Clinical Implications and Relationship to Stone Composition.

Authors:  Jessica E Paonessa; Ehud Gnessin; Naeem Bhojani; James C Williams; James E Lingeman
Journal:  J Urol       Date:  2016-03-30       Impact factor: 7.450

10.  Gram-stain plus MALDI-TOF MS (Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry) for a rapid diagnosis of urinary tract infection.

Authors:  Almudena Burillo; Belén Rodríguez-Sánchez; Ana Ramiro; Emilia Cercenado; Marta Rodríguez-Créixems; Emilio Bouza
Journal:  PLoS One       Date:  2014-01-22       Impact factor: 3.240

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