Literature DB >> 32723000

Are Weightbearing Restrictions Required After Microfracture for Isolated Chondral Lesions of the Knee? A Review of the Basic Science and Clinical Literature.

Deeptee Jain1, Elshaday S Belay2, John A Anderson3, William E Garrett2, Brian C Lau2.   

Abstract

CONTEXT: A strict rehabilitation protocol is traditionally followed after microfracture, including weightbearing restrictions for 2 to 6 weeks. However, such restrictions pose significant disability, especially in a patient population that is younger and more active. EVIDENCE ACQUISITION: An extensive literature review was performed through PubMed and Google Scholar of all studies through December 2018 related to microfracture, including biomechanical, basic science, and clinical studies. For inclusion, clinical studies had to report weightbearing status and outcomes with a minimum 12-month follow-up. STUDY
DESIGN: Clinical review. LEVEL OF EVIDENCE: Level 3.
RESULTS: Review of biomechanical and biology studies suggest new forming repair tissue is protected from shear forces of knee joint loading by the cartilaginous margins of the defect. This margin acts as a shoulder to maintain axial height and allow for tissue remodeling up to at least 12 months after surgery, well beyond current weight bearing restriction trends. A retrospective case-control study showed that weightbearing status postoperatively had no effect on clinical outcomes in patients who underwent microfracture for small chondral (<2 mm2) defects. In fact, 1 survey showed that many orthopaedic surgeons currently do not restrict weightbearing after microfracture.
CONCLUSION: This clinical literature review suggests that weightbearing restrictions may not be required after microfracture for isolated tibiofemoral chondral lesions of the knee. STRENGTH OF RECOMMENDATION TAXONOMY: C.

Entities:  

Keywords:  knee; microfracture; review; weightbearing

Mesh:

Year:  2020        PMID: 32723000      PMCID: PMC8167347          DOI: 10.1177/1941738120938662

Source DB:  PubMed          Journal:  Sports Health        ISSN: 1941-0921            Impact factor:   3.843


  36 in total

1.  Treatment of full thickness chondral lesions of the knee with microfracture in a group of athletes.

Authors:  Alberto Gobbi; Perrico Nunag; Konrad Malinowski
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2004-05-14       Impact factor: 4.342

2.  Arthroscopic microfracture of chondral defects of the knee: a comparison of two postoperative treatments.

Authors:  Richard A Marder; Gail Hopkins; Laura A Timmerman
Journal:  Arthroscopy       Date:  2005-02       Impact factor: 4.772

Review 3.  Current concepts in the rehabilitation following articular cartilage repair procedures in the knee.

Authors:  Michael M Reinold; Kevin E Wilk; Leonard C Macrina; Jeffrey R Dugas; E Lyle Cain
Journal:  J Orthop Sports Phys Ther       Date:  2006-10       Impact factor: 4.751

Review 4.  Surgical implants and technologies for cartilage repair and preservation of the knee.

Authors:  D Alex Stroh; Aaron J Johnson; Michael A Mont
Journal:  Expert Rev Med Devices       Date:  2011-05       Impact factor: 3.166

Review 5.  Animal models for cartilage regeneration and repair.

Authors:  Constance R Chu; Michal Szczodry; Stephen Bruno
Journal:  Tissue Eng Part B Rev       Date:  2010-02       Impact factor: 6.389

6.  Arthroscopic second-generation autologous chondrocyte implantation compared with microfracture for chondral lesions of the knee: prospective nonrandomized study at 5 years.

Authors:  Elizaveta Kon; Alberto Gobbi; Giuseppe Filardo; Marco Delcogliano; Stefano Zaffagnini; Maurilio Marcacci
Journal:  Am J Sports Med       Date:  2008-12-04       Impact factor: 6.202

7.  Patient satisfaction and outcome after microfracture of the degenerative knee.

Authors:  Bruce S Miller; J Richard Steadman; Karen K Briggs; Juan J Rodrigo; William G Rodkey
Journal:  J Knee Surg       Date:  2004-01       Impact factor: 2.757

Review 8.  Articular cartilage: injuries and potential for healing.

Authors:  J A Buckwalter
Journal:  J Orthop Sports Phys Ther       Date:  1998-10       Impact factor: 4.751

9.  Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial.

Authors:  Gunnar Knutsen; Lars Engebretsen; Tom C Ludvigsen; Jon Olav Drogset; Torbjørn Grøntvedt; Eirik Solheim; Torbjørn Strand; Sally Roberts; Vidar Isaksen; Oddmund Johansen
Journal:  J Bone Joint Surg Am       Date:  2004-03       Impact factor: 5.284

10.  Early events in cartilage repair after subchondral bone microfracture.

Authors:  David D Frisbie; Julia T Oxford; Louise Southwood; Gayle W Trotter; William G Rodkey; J Richard Steadman; Jennifer L Goodnight; C Wayne McIlwraith
Journal:  Clin Orthop Relat Res       Date:  2003-02       Impact factor: 4.176

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  1 in total

1.  Impact of Early Weightbearing After Ankle Arthroscopy and Bone Marrow Stimulation for Osteochondral Lesions of the Talus.

Authors:  Richard M Danilkowicz; Nathan L Grimm; Gloria X Zhang; Thomas A Lefebvre; Brian Lau; Samuel B Adams; Annunziato Amendola
Journal:  Orthop J Sports Med       Date:  2021-09-13
  1 in total

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