Literature DB >> 32721912

Stem cell therapy: a potential for the perils of pancreatitis.

Harleen Chela1, Bhupinder S Romana1, Markandeya Madabattula1, Abdulmajeed A Albarrak1, Mohamad H Yousef1, Sami Samiullah1, Veysel Tahan1.   

Abstract

Acute and chronic pancreatitis carry a significant disease burden and there is no definite treatment that exists for either. They are associated with local and systemic inflammation and lead to numerous complications. Stem cell therapy has been explored for other disease processes and is a topic of research that has gained momentum with regards to implications for acute and chronic pancreatitis. They not only carry the potential to aid in regeneration but also prevent pancreatic injury as well as injury of other organs and hence the resultant complications. Stem cells appear to have immunomodulatory properties and clinical potential as evidenced by numerous studies in animal models. This review article discusses the types of stem cells commonly used and the properties that show promise in the field of pancreatitis.

Entities:  

Year:  2020        PMID: 32721912      PMCID: PMC7433995          DOI: 10.5152/tjg.2020.19143

Source DB:  PubMed          Journal:  Turk J Gastroenterol        ISSN: 1300-4948            Impact factor:   1.852


  71 in total

Review 1.  Acute pancreatitis: models, markers, and mediators.

Authors:  Jill Granger; Daniel Remick
Journal:  Shock       Date:  2005-12       Impact factor: 3.454

Review 2.  Allogeneic and xenogeneic transplantation of adipose-derived stem cells in immunocompetent recipients without immunosuppressants.

Authors:  Ching-Shwun Lin; Guiting Lin; Tom F Lue
Journal:  Stem Cells Dev       Date:  2012-07-03       Impact factor: 3.272

3.  Adipose Stem Cell Therapy Mitigates Chronic Pancreatitis via Differentiation into Acinar-like Cells in Mice.

Authors:  Zhen Sun; Wenyu Gou; Do-Sung Kim; Xiao Dong; Charlie Strange; Yu Tan; David B Adams; Hongjun Wang
Journal:  Mol Ther       Date:  2017-08-04       Impact factor: 11.454

4.  Reduction of fibrosis in dibutyltin dichloride-induced chronic pancreatitis using rat umbilical mesenchymal stem cells from Wharton's jelly.

Authors:  Chun-Hua Zhou; Mei-Lin Li; Ai-Lan Qin; Sheng-Xiang Lv; Xiao-Yan Zhu; Lin-Yun Li; Yun Dong; Chuang-Ying Hu; Duan-Min Hu; Shao-Feng Wang
Journal:  Pancreas       Date:  2013-11       Impact factor: 3.327

5.  Adipose tissue-derived mesenchymal stromal cells efficiently differentiate into insulin-producing cells in pancreatic islet microenvironment both in vitro and in vivo.

Authors:  Erdal Karaoz; Alparslan Okcu; Zehra Seda Ünal; Cansu Subasi; Ozlem Saglam; Gokhan Duruksu
Journal:  Cytotherapy       Date:  2013-02-04       Impact factor: 5.414

6.  Functional cardiomyocytes derived from human induced pluripotent stem cells.

Authors:  Jianhua Zhang; Gisela F Wilson; Andrew G Soerens; Chad H Koonce; Junying Yu; Sean P Palecek; James A Thomson; Timothy J Kamp
Journal:  Circ Res       Date:  2009-02-12       Impact factor: 17.367

7.  Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.

Authors:  Xiaobo Xu; Joke D'Hoker; Geert Stangé; Stefan Bonné; Nico De Leu; Xiangwei Xiao; Mark Van de Casteele; Georg Mellitzer; Zhidong Ling; Danny Pipeleers; Luc Bouwens; Raphael Scharfmann; Gerard Gradwohl; Harry Heimberg
Journal:  Cell       Date:  2008-01-25       Impact factor: 41.582

8.  Role of bone marrow-derived cells in experimental chronic pancreatitis.

Authors:  F Marrache; S Pendyala; G Bhagat; K S Betz; Z Song; T C Wang
Journal:  Gut       Date:  2008-03-26       Impact factor: 31.793

Review 9.  (Mesenchymal) Stem Cell-Based Therapy in Cisplatin-Induced Acute Kidney Injury Animal Model: Risk of Immunogenicity and Tumorigenicity.

Authors:  Ž Večerić-Haler; A Cerar; M Perše
Journal:  Stem Cells Int       Date:  2017-12-12       Impact factor: 5.443

10.  Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents.

Authors:  Sheryl M Southard; Rama P Kotipatruni; William L Rust
Journal:  PLoS One       Date:  2018-09-05       Impact factor: 3.240

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  1 in total

1.  The Role of Mesenchymal Stem Cells with Ascorbic Acid and N-Acetylcysteine on TNF-α, IL 1β, and NF-κβ Expressions in Acute Pancreatitis in Albino Rats.

Authors:  Dalia Abdelhafez; Elshimaa Aboelkomsan; Abir El Sadik; Noha Lasheen; Sara Ashur; Amal Elshimy; George N B Morcos
Journal:  J Diabetes Res       Date:  2021-10-16       Impact factor: 4.011

  1 in total

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