Rafael S Cires-Drouet1, Minerva Mayorga-Carlin1, Shahab Toursavadkohi1,2, Rachel White1, Emily Redding1, Frederick Durham1, Kathleen Dondero3, Steven J Prior4,5,6, John D Sorkin4,5, Brajesh K Lal1,2. 1. Division of Vascular Surgery, Department of Surgery, University of Maryland, Baltimore, MD, USA. 2. Vascular Service, Veterans Affairs Medical Center, Baltimore, MD, USA. 3. Department of Kinesiology, Towson University, Baltimore, MD, USA. 4. Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA. 5. Baltimore VA Geriatrics Research, Education, and Clinical Center, Baltimore Veterans Affairs Medical Center, Baltimore, MD, USA. 6. Department of Kinesiology, University of Maryland School of Public Health, College Park, MD, USA.
Abstract
OBJECTIVE: The role of exercise therapy after acute pulmonary embolism (PE) is unknown. Exercise therapy is safely used after myocardial infarction and chronic obstructive pulmonary disease. The aim of this study was to investigate the safety of exercise therapy after acute PE. METHODS: We implemented a 3-month exercise program after acute PE. Outcomes were death, bleeding, readmissions, recurrent events, changes in peak VO2 and quality of life (QoL). RESULTS: A total of 23 patients were enrolled and received anticoagulation; no adverse events were reported during the exercise period. One death, 1 DVT and 5 readmissions were reported due to non-exercise related reasons. Functional capacity improved as evidenced by an increased peak VO2 at 3 months (+3.9 ± 5.6 mL/kg/min; p = 0.05). Improvement in QoL was observed at 6-months on the functional (+17.0 ± 22.6, p = 0.03) and physical health factor scales (+0.9 ± 4.6, p = 0.03). CONCLUSION: Exercise therapy is feasible and safe in appropriately anticoagulated patients after PE.
OBJECTIVE: The role of exercise therapy after acute pulmonary embolism (PE) is unknown. Exercise therapy is safely used after myocardial infarction and chronic obstructive pulmonary disease. The aim of this study was to investigate the safety of exercise therapy after acute PE. METHODS: We implemented a 3-month exercise program after acute PE. Outcomes were death, bleeding, readmissions, recurrent events, changes in peak VO2 and quality of life (QoL). RESULTS: A total of 23 patients were enrolled and received anticoagulation; no adverse events were reported during the exercise period. One death, 1 DVT and 5 readmissions were reported due to non-exercise related reasons. Functional capacity improved as evidenced by an increased peak VO2 at 3 months (+3.9 ± 5.6 mL/kg/min; p = 0.05). Improvement in QoL was observed at 6-months on the functional (+17.0 ± 22.6, p = 0.03) and physical health factor scales (+0.9 ± 4.6, p = 0.03). CONCLUSION: Exercise therapy is feasible and safe in appropriately anticoagulated patients after PE.
Entities:
Keywords:
Pulmonary embolism; Quality of life assessment; Venous thromboembolism
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