Literature DB >> 32715746

The controversial role of IL-6 in adipose tissue on obesity-induced dysregulation of glucose metabolism.

Stephan Wueest1,2, Daniel Konrad1,2,3.   

Abstract

Interleukin (IL)-6 is a pleotropic cytokine with various physiological and pathophysiological functions in different cells and tissues. In cells residing within white adipose tissue, several, and sometimes conflicting, IL-6 actions have been described in the development of obesity-associated derangements of glucose metabolism. Herein, we aim to summarize opposing findings and discuss recent evidence that IL-6 signaling in adipose tissue is regulated in a depot and cell-specific manner.

Entities:  

Keywords:  adipose tissue; interleukin-6; obesity

Year:  2020        PMID： 32715746     DOI： 10.1152/ajpendo.00306.2020

Source DB:  PubMed          Journal:  Am J Physiol Endocrinol Metab        ISSN： 0193-1849            Impact factor:   4.310


  12 in total

1.  The association of measures of body shape and adiposity with incidence of cardiometabolic disease from an ageing perspective.

Authors:  Fleur L Meulmeester; Ko Willems van Dijk; Simon P Mooijaart; Diana van Heemst; Raymond Noordam
Journal:  Geroscience       Date:  2022-09-21       Impact factor: 7.581

Review 2.  Adipose tissue macrophages and atherogenesis - a synergy with cholesterolaemia.

Authors:  R Poledne; I Králová Lesná
Journal:  Physiol Res       Date:  2021-12-30       Impact factor: 2.139

Review 3.  Interleukin 6 as an energy allocator in muscle tissue.

Authors:  Timothy M Kistner; Bente K Pedersen; Daniel E Lieberman
Journal:  Nat Metab       Date:  2022-02-24

4.  Autologous Human Immunocompetent White Adipose Tissue-on-Chip.

Authors:  Julia Rogal; Julia Roosz; Claudia Teufel; Madalena Cipriano; Raylin Xu; Wiebke Eisler; Martin Weiss; Katja Schenke-Layland; Peter Loskill
Journal:  Adv Sci (Weinh)       Date:  2022-04-24       Impact factor: 17.521

5.  Development of metabolic inflammation during pre-hibernation fattening in 13-lined ground squirrels (Ictidomys tridecemlineatus).

Authors:  Michelle M Sonsalla; Santidra L Love; Laurana J Hoh; Lauren N Summers; Hannah M Follett; Aminata Bojang; Khrystyne N Duddleston; Courtney C Kurtz
Journal:  J Comp Physiol B       Date:  2021-06-24       Impact factor: 2.200

Review 6.  Innate Immune Cells in the Adipose Tissue in Health and Metabolic Disease.

Authors:  Zoi Michailidou; Mario Gomez-Salazar; Vasileia Ismini Alexaki
Journal:  J Innate Immun       Date:  2021-04-13       Impact factor: 7.349

7.  IL-6 Receptor Blockade Increases Circulating Adiponectin Levels in People with Obesity: An Explanatory Analysis.

Authors:  Stephan Wueest; Eleonora Seelig; Katharina Timper; Mark P Lyngbaek; Kristian Karstoft; Marc Y Donath; Helga Ellingsgaard; Daniel Konrad
Journal:  Metabolites       Date:  2021-01-29

Review 8.  Sympathetic nerve-adipocyte interactions in response to acute stress.

Authors:  Gabryella S P Santos; Alinne C Costa; Caroline C Picoli; Beatriz G S Rocha; Sheu O Sulaiman; Debora C Radicchi; Mauro C X Pinto; Miguel L Batista; Jaime H Amorim; Vasco A C Azevedo; Rodrigo R Resende; Niels O S Câmara; Akiva Mintz; Alexander Birbrair
Journal:  J Mol Med (Berl)       Date:  2021-11-04       Impact factor: 4.599

Review 9.  The Obese Brain: Mechanisms of Systemic and Local Inflammation, and Interventions to Reverse the Cognitive Deficit.

Authors:  Verónica Salas-Venegas; Rosa Pamela Flores-Torres; Yesica María Rodríguez-Cortés; Diego Rodríguez-Retana; Ricardo Jair Ramírez-Carreto; Luis Edgar Concepción-Carrillo; Laura Josefina Pérez-Flores; Adriana Alarcón-Aguilar; Norma Edith López-Díazguerrero; Beatriz Gómez-González; Anahí Chavarría; Mina Konigsberg
Journal:  Front Integr Neurosci       Date:  2022-03-29

Review 10.  Metabolic factors in the regulation of hypothalamic innate immune responses in obesity.

Authors:  Andrew Folick; Rachel T Cheang; Martin Valdearcos; Suneil K Koliwad
Journal:  Exp Mol Med       Date:  2022-04-26       Impact factor: 12.153
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