OBJECTIVE: To quantify pregnancy outcomes and the frequency and cause of infertility among women with psoriatic arthritis. METHODS: Women with psoriatic arthritis aged 20-50 years completed a questionnaire about prior pregnancies, infertility, and family planning. Patient-reported pregnancy outcomes were validated by chart review. RESULTS: In 40 women with psoriatic arthritis, 67% of 70 pregnancies were live births. Patient-reported preterm birth and preeclampsia were more common after psoriatic arthritis diagnosis but were significantly over-reported. Most women reported no or mild joint pain during pregnancy and few took medications for psoriatic arthritis. Infertility was reported by 36% of women who were ever pregnant or ever tried to become pregnant, primarily due to polycystic ovary syndrome. CONCLUSION: The patient-reported pregnancy outcomes in this retrospective survey were not supported by chart review, making prospective studies essential to understand the interaction of psoriatic arthritis and pregnancy. Infertility, particularly due to polycystic ovary syndrome, appears to be an important issue in this population.
OBJECTIVE: To quantify pregnancy outcomes and the frequency and cause of infertility among women with psoriatic arthritis. METHODS: Women with psoriatic arthritis aged 20-50 years completed a questionnaire about prior pregnancies, infertility, and family planning. Patient-reported pregnancy outcomes were validated by chart review. RESULTS: In 40 women with psoriatic arthritis, 67% of 70 pregnancies were live births. Patient-reported preterm birth and preeclampsia were more common after psoriatic arthritis diagnosis but were significantly over-reported. Most women reported no or mild joint pain during pregnancy and few took medications for psoriatic arthritis. Infertility was reported by 36% of women who were ever pregnant or ever tried to become pregnant, primarily due to polycystic ovary syndrome. CONCLUSION: The patient-reported pregnancy outcomes in this retrospective survey were not supported by chart review, making prospective studies essential to understand the interaction of psoriatic arthritis and pregnancy. Infertility, particularly due to polycystic ovary syndrome, appears to be an important issue in this population.
Authors: Marianne Coolman; Christianne J M de Groot; Vincent W Jaddoe; Albert Hofman; Hein Raat; Eric A P Steegers Journal: J Clin Epidemiol Date: 2010-03-02 Impact factor: 6.437
Authors: Floranne C Wilson; Murat Icen; Cynthia S Crowson; Marian T McEvoy; Sherine E Gabriel; Hilal Maradit Kremers Journal: J Rheumatol Date: 2009-01-22 Impact factor: 4.666
Authors: Luis Fernando Perez-Garcia; Esther Röder; Robbert J Goekoop; Johanna M W Hazes; Marc R Kok; Hieronymus T W Smeele; Ilja Tchetverikov; Annette H M van der Helm-van Mil; Jos H van der Kaap; Petra Kok; Bouwe P Krijthe; Radboud J E M Dolhain Journal: Ann Rheum Dis Date: 2021-08-09 Impact factor: 19.103