| Literature DB >> 32711825 |
Hany Elgamal1, Markus M Luedi2, Joerg Karl Ender3, Massimiliano Meineri4.
Abstract
Oral anticoagulants (OACs) are a class of medications commonly used in the long-term management of patients at risk of thrombosis. They include warfarin and direct oral anticoagulants (DOACs). The aging of the population and improvements in perioperative care have led to an increase in the number of patients on OACs and presenting for different types of elective and emergency surgery. Perioperative management of OACs constitutes a unique challenge. It is based on the quantification of a patient's individual hemorrhagic and thrombotic risk together with the intrinsic surgical bleeding risk. We reviewed current guidelines to define effective discontinuation of OACs, the need for bridging with different anticoagulants, and post-surgery OACs re-initiation. We also discussed the option for acute reversal of anticoagulation.Entities:
Keywords: direct oral anticoagulants; oral anticoagulants; perioperative management; surgery; warfarin
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Year: 2020 PMID: 32711825 DOI: 10.1016/j.bpa.2020.06.002
Source DB: PubMed Journal: Best Pract Res Clin Anaesthesiol ISSN: 1521-6896